COVID-19, Hemoptysis, Lung Cancer, Lung TB
Conditions
Brief summary
This study will determine the outcomes of anatomic lung resections in patients who recovered from coronavirus disease 2019 (COVID-19) disease by describing the morbidity and mortality as well as the length of postoperative hospital stay.
Detailed description
This study will be conducted at the Lung Center of the Philippines. The study design is a retrospective case series implemented via chart review. Online and written patient records will be reviewed to determine the baseline patient characteristics and the preoperative outcomes. Patients who recovered from COVID-19 will be selected from those who underwent anatomic lung resection from June 1, 2020 to May 31, 2022. This study will be done in accordance with the Helsinky Declaration and Good Clinical Practice Guidelines, and will be subject for approval of the institutional Ethics and Technical Review Boards. Descriptive statistics will be used to describe patient characteristics and perioperative outcomes.
Interventions
PROCEDUREanatomic lung resection
includes minimally invasive or open lung segmentectomy, lobectomy, bilobectomy and pneumonectomy
Sponsors
Lung Center of the Philippines
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* underwent anatomic lung resection * previous COVID-19 infection documented by nasopharyngeal swab RT-PCR or GeneXpert * with negative nasopharyngeal swab RT-PCR or GeneXpert prior to lung resection
Exclusion criteria
* with incomplete patient records
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality rate | perioperative period (up to 30 days after anatomic lung resection) | proportion of patients who died due to perioperative complications |
| Major complication rate | perioperative period (up to 30 days after anatomic lung resection) | proportion of patients who develop acute kidney injury, acute myocardial infarction, acute respiratory distress syndrome (ARDS), acute respiratory failure, atelectasis requiring intervention, bronchopleural fistula, empyema thoracis, hemothorax, pneumonia, stroke or venous thromboembolism |
| Minor complication rate | perioperative period (within 30 days after anatomic lung resection) | proportion of patients who develop atrial fibrillation, pneumothorax or prolonged air leak |
| Length of postoperative hospital stay | perioperative period (up to 30 days after anatomic lung resection) | time duration from surgery to discharge order |
Countries
Philippines
Outcome results
None listed