Ischemic Neuropathy, Rare Neuropathy
Conditions
Brief summary
Neuropathies are defined as the clinical, electrical, biological and histological manifestations of peripheral neuron damage. They represent a heterogeneous group of disorders and are responsible for disabling sensory and motor disorders. Their diagnosis is based on a set of clinical arguments confirmed by the electromyogram. This allows to specify the site of the damage, its severity, and to follow the evolution of the disease. To date, the diagnosis of peripheral nerve injury secondary to occlusion of arterial trunks is rarely evoked; its clinical, electromyographic and prognostic characteristics are poorly known. Indeed, the rare cases reported in the literature are from vascular specialties, with little data on neurological symptoms, neurophysiological diagnostic elements and prognosis. However, these unrecognized and underdiagnosed neuropathies are sometimes indicative of severe vascular damage for which urgent management is necessary. Neurological symptoms should then be treated as warning signs and the correct recognition of the early ischemic vascular etiology may lead to an optimized medical management. The objectives of this study will be to describe the clinical presentation of these neuropathies, to discuss their electrophysiological diagnostic characteristics, to compare the demographic data with those from the literature, and to evaluate the functional prognosis of these attacks. A better knowledge of this rare etiology of neuropathy would allow to better inform the patients and to optimize the diagnostic and therapeutic management.
Interventions
None listed
Sponsors
Fondation Hôpital Saint-Joseph
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient whose age ≥ 18 years * Patient hospitalized or seen in neurophysiological consultation/exploration in the Neurology Department within the Groupe Hospitalier Paris Saint-Joseph * Diagnosis of acute or subacute peripheral nerve ischemia * French speaking patient
Exclusion criteria
* Patient with impaired comprehension making it impossible to understand the protocol * Patient under guardianship or curatorship * Patient under court protection * Patient deprived of liberty * Patient or relative who objects to the use of his/her data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Characteristics of patients according to their neurophysiological impairment | Month 1 | This outcome corresponds to the description of patient demographics and cardiovascular history/risk factors. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Prognostic factors for functional recovery | Month 1 | This outcome corresponds to the the prognosis of the disease (return to the previous state/persistence of a partial deficit/persistence of symptoms) and the time to improvement. |
Countries
France
Outcome results
None listed