Evaluation of Different Surgical Approaches Used for Conservative Management of Placenta Accreta Spectrum in Sohag University Hospital

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05510076

Enrollment

Registered

2022-08-22

Start date

2022-08-01

Completion date

2023-06-30

Last updated

2022-08-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Placenta Accreta Spectrum

Brief summary

The objective of this study is to evaluate different intra-operative procedures to control bleeding in cases of PAS disorders aiming to determine the best procedure regarding maternal morbidity and mortality post-operatively, and to evaluate the long-term effects of conservative management of PAS disorders.

Detailed description

The term placenta accreta spectrum (PAS), formerly known as morbidly adherent placenta or abnormally invasive placenta, refers to the aberrant trophoblast invasion of all or a portion of the placenta into the myometrium of the uterus. according to the depth of the villous invasion into the myometrium, the spectrum is assorted into three groups: placenta accreta (villi attach to the myometrium without invading it), placenta increta (villi infiltrate the myometrium), and placenta percreta (villi pierce through the uterine serosa and may infiltrate the surrounding tissues). The optimal strategy for managing PAS disorders remains debatable. Conservative management of PAS disorders includes all techniques aimed at preserving the uterus. Because intraoperative bleeding from PAS disorders is frequently massive and dramatic, causing severe maternal morbidity and mortality, it is essential to have a well-planned, effective, and rapid approach to this surgical challenge.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

No minimum to 51 Years

Healthy volunteers

Yes

Inclusion criteria

* Women with at least one previous caesarean section and suspected PAS disorders by imaging studies

Exclusion criteria

* Patients with intraoperative spontaneous placental separation. * Patients with a preoperative diagnosis of placenta percreta who chose to have an elective hysterectomy. * Any other associated uterine pathology requiring hysterectomy. * Coagulation disorders.

Design outcomes

Primary

Measure	Time frame	Description
successful intervention procedure	1 day	Preservation of the uterus
maternal mortality and morbidity	6 weeks	ICU admission, need of re-exploration, drop of hemoglobin and hematocrit values, massive blood transfusion, bladder and/ or ureteric injury, coagulopathy, infection and hospital re-admission within 6 weeks

Countries

Egypt

Contacts

Primary ContactAbdAllah Refaat

abdallah.refaat@med.sohag.edu.eg+201141519467

Backup ContactAbdAllah Refaat

abdoscopy@gmail.com+01555518179

Outcome results