Gynecologic Disease
Conditions
Brief summary
Acetaminophen and ibuprofen has been safely used for a long time and reduces postoperative pain and opioid dosages. Investigators are planning to compare the efficacy of 1) acetaminophen only and 2) acetaminophen and ibuprofen combination at postoperative pain after laparoscopic gynecologic surgery.
Detailed description
Acetaminophen and ibuprofen has been safely used for a long time and reduces postoperative pain and opioid dosages. Investigators are planning to compare the efficacy of 1) acetaminophen 1g only and 2) the combination of acetaminophen 1g and ibuprofen 300mg at postoperative pain after laparoscopic gynecologic surgery. Some recovery valuables such as the postoperative pain and opioid requirements will be assessed.
Interventions
DRUGAcetaminophen
acetaminophen 1g iv dripping at end of surgery
DRUGIbuprofen
ibuprofen 300mg iv dripping at end of surgery
Sponsors
The Catholic University of Korea
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients scheduled gynecologic laparoscopic surgery
Exclusion criteria
1. Refusal to be enrolled in the study 2. Emergency surgery 3. On chronic pain medications 4. Psychiatric disorders 5. Pregnant, lactating women 6. Allergy or contraindication to the medication drugs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| postoperative pain | during 30 minutes after surgery | the maximal postoperative pain severity using pain scale (0=no pain; 10=the worst pain) |
Countries
South Korea
Contacts
Primary Contactyoungeun moon, MD, PhD
Backup Contactjungmin gu, MD
Outcome results
None listed