Age-Related Macular Degeneration, Photobiomodulation
Conditions
Keywords
choroidal neovascular membrane
Brief summary
The study will investigate the effect of photobiomodulation treatment on the risk of developing late age related macula degeneration (AMD) in the study eye in patients with wet AMD in the fellow eye.
Interventions
DEVICEValeda machine
Photobiomodulation treatment with Valeda machine will be applied every six months for 2 years in patients with dry age related macula degeneration.
Sponsors
Oslo University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients with dry AMD in the study eye and wet AMD in the control eye
Exclusion criteria
* Geographic atrophy of the central macular region at enrolment * Previous/ active wet AMD in the study eye * A history of epilepsy * Retinal diseases apart from AMD * Significant media opacities * Cataracts worse than grade 2 (LOCS III classification) * Change in AREDS 2 supplements (vitamins) 1 month before the study and during the study trial was allowed. * Ongoing systemic medications that are photosensitizing (e.g. tetracyclins) * Systemic medications during the last 6 months that can cause deposits in the macular region (hydroxychloroquine, amiodarone) * Unable to give informed consent * Unable to cooperate with the treatment and follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of patients that develope late AMD in the study eye compared with control after 3 years of follow-up | 3 years |
Outcome results
None listed