Epilepsy
Conditions
Brief summary
Study the mechanisms underlying action recognition and execution
Detailed description
Subjects will participate in a task where they have to either 1. Perform a movement 2. Observe an actor performing a movement There are three types of actions including different kinematics and grip types The goal is to compare the neural circuits activated by action execution versus action observation.
Interventions
BEHAVIORALMechanisms of action perception and execution
Study the mechanisms of action perception and execution
Sponsors
Boston Children's Hospital
Study design
Observational model
OTHER
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
14 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients with pharmacologically intractable epilepsy
Exclusion criteria
* Any situation that may put the patient at risk
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Selectivity for kinematics and movement type in neurophysiological responses | Through study completion, an average of 2 years. | Measure intracranial field potentials (in microvolts) in the gamma frequency band through neurophysiological responses comparing neural responses during action perception versus execution. We will assess selectivity for kinematics for each movement type |
| Evoked responses by action execution | Through study completion, an average of 2 years. | Measure intracranial field potentials (in microvolts) in the gamma frequency band through neurophysiological responses comparing neural responses during action perception versus execution. We will quantify responses evoked by action execution |
| Evoked responses by action observation | Through study completion, an average of 2 years. | Measure intracranial field potentials (in microvolts) in the gamma frequency band through neurophysiological responses comparing neural responses during action perception versus execution. We will quantify responses evoked by action observation |
Countries
United States
Contacts
Primary ContactGabriel Kreiman, PhD
Outcome results
None listed