Resting Energy Expenditure
Conditions
Keywords
Resting energy expenditure, Resting metabolic rate, Ambient temperature, Environmental temperature
Brief summary
The aim of this study is to investigate the influence of four different ambient temperatures (18, 22, 28, 38°C) on the resting energy expenditure of healthy adults by respiratory gas analysis. It is assumed that the resting energy expenditure is higher at 18°C and 38°C than at the temperatures in between.
Detailed description
In a crossover-design, 32 healthy men and women participate in four interventions. Each intervention includes a measurement of the resting energy expenditure by respiratory gas analysis at a different ambient temperature (18,22, 28 and 38°C). During this time body core- and surface temperature are assessed, as well as body composition via bioelectrical impedance analysis. For each participant the four individual study days take place in a randomized order on consecutive weekdays within a week.
Interventions
OTHERRespiratory analysis at cold temperature
Respiratory analysis at an ambient temperature of 18°C
OTHERRespiratory analysis at room temperature
Respiratory analysis at an ambient temperature of 22°C
OTHERRespiratory analysis at thermoneutral temperature
Respiratory analysis at an ambient temperature of 28°C
OTHERRespiratory analysis at hot temperature
Respiratory analysis at an ambient temperature of 38°C
Sponsors
DLR German Aerospace Center
University of Bonn
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI: 18,5 - 24,9 kg/m2 * metabolically healthy
Exclusion criteria
* smoking * low or high blood pressure * dyslipidemia * insulin resistance or diabetes mellitus type 1 or type 2 * gastrointestinal diseases (e.g. food intolerances or allergies) * liver, kidney and/or thyroid diseases * hepatitis B or C, HIV Infection * chronic inflammatory diseases * disordered eating * psychological diseases * alcohol and/or drug abuse * use of medication * pregnancy or lactating * participation in another intervention study * women: irregular menstrual cycle * more than 6 h of sports per week
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Resting Energy Expenditure | 20 minutes | Volume of inhaled oxygen (VO2) in L/min and exhaled carbon dioxide (VCO2) in L/min |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body core temperature | 20 minutes | Body core temperature: assessed every ten seconds during respiratory analysis (°C) |
| Body surface temperature | 20 minutes | Body surface temperature: assessed every ten seconds during respiratory analysis (°C) |
| Body composition | 5 minutes (after respiratory analysis) | assessed daily via bioelectrical impedance analysis after respiratory analysis (FFM (kg), FM (kg)) |
| Blood pressure | 10 minutes (at beginning of study day) | assessed daily before respiratory analysis (mmHg) |
Countries
Germany
Outcome results
None listed