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Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD

Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05504993
Enrollment
92
Registered
2022-08-17
Start date
2018-01-01
Completion date
2022-01-01
Last updated
2022-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Exacerbation of COPD, Chronic Obstructive Lung Disease, Comorbidities and Coexisting Conditions

Brief summary

INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too. Comorbidity indexes can be used for recognition of comorbidities while managing COPD patients. In the present study, it is aimed to compare comorbidity indexes such as Charlson Comorbidity Index, COMCOLD and COTE in the matter of exacerbation frequency. METHOD: Subjects hospitalized for AECOPD, admitted to the study. Exacerbation severity, frequency, further exacerbations for a 1-year period in the follow-up period and CCI, COMCOLD and COTE scores were recorded. High and low comorbidity groups were compared for AECOPD frequency, severity, and further exacerbations.

Interventions

OTHERFrequency of AECOPD

No intervention has been applied. 92 COPD patients divided into 2 groups according to their comorbidity level. Than these groups were compared for their AECOPD frequency

Sponsors

Ankara University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* COPD patients * Admitted to the ward for AECOPD

Exclusion criteria

* Not giving informed consent * Unable to perform PFT * Lost to follow-up

Design outcomes

Primary

MeasureTime frameDescription
Frequency of AECOPD1 yearFrequency of AECOPD in the last one year

Secondary

MeasureTime frameDescription
Having at least one severe AECOPD1 yearhaving at least one severe AECOPD in the last year
Frequency of AECOPD for the next one year1 yearthe number of AECOPD for 1 year period from the preceding admission, regardless of severity

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026