Multiple Sclerosis
Conditions
Keywords
Multiple Sclerosis, Trunk control, Balance, Outcome measure
Brief summary
The current project will fill a knowledge gap in the follow-up of people with Multiple Sclerosis (MS) with mild and moderate disability levels, with the purpose to assess the adequacy of measurement tools for trunk control and balance, functions that are pre-requisites for optimal performance in everyday physical activities.
Detailed description
Trunk control and balance, necessary for daily activities, are frequently impaired in people with MS. Adequate measurement tools for clinical- and research purposes are thus warranted. In this study two measurement tools will be explored: 1. The Trunk Impairment scale - modified Norwegian version (TIS-modNV), which has demonstrated high validity and reliability in individuals with stoke (Gjelsvik et al., 2012), however its properties has not yet been assessed in people with MS. Concurrent validity with a balance scale, the Mini-Balance Evaluation Systems Test (Mini-BESTest), will be assessed as well as its inter- and intra-rater reliability. 2. The AMTI Accugait Optimized™ multi-axis force platform (AMTI, Inc., Newton, MA) will be examined as there is a lack of studies measuring its properties within the MS population. A validity assessment of this tool will be included in this measurement study. This study is two-parted, each with a separate aim: Aim part 1: To determine the validity and reliability of the TIS-modNV across mild and moderate disability levels in the MS population. Aim part 2: To determine the concurrent validity of the AMTI AccuGait OptimizedTM force plate system compared to the Mini-BESTest across mild and moderate disability levels in the MS population.
Interventions
None listed
Sponsors
Nord University
Helse Nord
Nordlandssykehuset HF
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* MS diagnosis (McDonalds criteria) * EDSS= 0-6.5 * Ability to walk minimum 6 meters
Exclusion criteria
* People will be excluded if not being able to follow test instructions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The modified Trunk Impairment Scale - Norwegian version (TIS-modNV) | 01 January 2023 | TIS-modNV is a six-item ordinal scale measuring impairments of trunk control. The total score ranges between 0-16, where 16 is the best score in trunk control. The scale is developed for and valid and reliable for people with stroke. |
| AMTI AccuGait OptimizedTM (Advanced Mechanical technology, Inc., Watertown, USA) multi-axis force plate system | 01 January 2023 | Force- platform assessing different domains of balance (ie. centre of pressure, sway) in bi- and unipedal standing with eyes open and with eyes closed. |
Other
| Measure | Time frame | Description |
|---|---|---|
| The Mini Balance Evaluation Systems Test (Mini-BESTest) | 01 January 2023 | Mini-BESTest is a 14-item ordinal scale, measuring balance in standing and walking. The total scores ranges from 0-28, were 28 is the best score of balance performance. The Norwegian translation of the test is valid and reliable for people with MS. |
| Expanded Disability Status Scale (EDSS) | 01 January 2023 | EDSS is a method of quantifying and monitoring disability in people with MS on a scale from 0-10 and is widely used in clinic and research. A total score of 0 describes no disability and a score 10 describes death due to MS. EDSS scores 0-6.5 (the levels included in this study) encompasses individuals with normal neurological exam/fully ambulatory (score 0) to individuals requiring a walking aids (cane, crutch) to walk about 20m without resting (score 6.5). |
Countries
Norway
Contacts
Primary ContactEllen Christin Arntzen, PHD
Backup ContactStine Susanne Haakonsen Dahl, MSc
Outcome results
None listed