Attention-deficit/Hyperactivity Disorder
Conditions
Brief summary
The association between levels of zonulin and occludin and behavioral/emotional problems in children with ADHD are investigated.
Detailed description
Inclusion criteria for the ADHD group are (a) newly diagnosed ADHD (b) no prior psychotropic treatment for ADHD or any psychiatric disorder (c) age 6-12 years. Exclusion criteria were: (a) history of history of inflammatory/noninflammatory, metabolic, or autoimmune disease (b) any special diet history within the past year (c) use of corticosteroids or regular intake of medication in the last 6 months, (d) body mass index (BMI) \[kg/m2\] \> 30), and (e) cognitive deficits by developmental history.
Interventions
DIAGNOSTIC_TESTZonulin
Serum zonulin level
DIAGNOSTIC_TESTOccludin
Serum occludin level
Sponsors
Ataturk University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
6 Years to 12 Years
Healthy volunteers
Yes
Inclusion criteria
* (a) newly diagnosed ADHD * (b) no prior psychotropic treatment for ADHD or any psychiatric disorder * (c) age 6-12 years.
Exclusion criteria
* (a) history of history of inflammatory/noninflammatory, metabolic, or autoimmune disease * (b) any special diet history within the past year * (c) use of corticosteroids or regular intake of medication in the last 6 months, * (d) body mass index (BMI) \[kg/m2\] \> 30), * (e) cognitive deficits by developmental history
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Zonulin level | 1 month | Serum Zonulin level after psychiatric interview |
| Occludin level | 1 month | Serum Occludin level after psychiatric interview |
Countries
Turkey (Türkiye)
Outcome results
None listed