Lidocaine Spray for Pain Control in Rib Fractures

Comparison of the Analgesic Efficacy of Lidocaine Spray Versus Tramadol and Fentanyl for Pain Control in Rib Fractures: A Prospective, Randomized, Controlled and Open-label Study

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05500677

Enrollment

Registered

2022-08-15

Start date

2021-06-01

Completion date

2021-11-30

Last updated

2022-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rib Fractures, Analgesia

Keywords

Analgesia, Fentanyl, Lidocaine spray, Rib fracture, Tramadol

Brief summary

In this study, we aimed to compare the analgesic efficacy of lidocaine spray with tramadol hydrochloride and fentanyl citrate in rib fractures.

Detailed description

Patients over the age of 18 who came to our emergency department with blunt chest trauma were divided into three groups. Groups was created from patients who were given lidocaine 10% spray (local), i.v. 100 mg of tramadol and i.v. fentanyl 50 mcg. A total of 48 patients, each of whom were 16, were included in the study. Numerical rating scale (NRS) pain scores of the patients at baseline, 15th, 30th and 60th minutes were compared. These scores and the amount of falls at follow-up were analyzed comparatively between the 3 groups.

Interventions

DRUGLidocaine topical

Lidocaine spray, which is a quick and easy-to-use topical local anesthetic, will be applied as a puff to the painful area.

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Masking description

open label study

Intervention model description

Pain control in rib fracture

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Open conscious * Oriented and cooperative * Blunt thoracic trauma and rib fracture * Numerical rating scale (NRS) was 5 or higher

Exclusion criteria

* Patients who refused to participate in the study * Detected or suspected pregnancy * Known history of allergy or other adverse reaction to the drugs used in the study * History of sedative drug use or drug addiction * Analgesic use within 6 hours of admission to the emergency department * Needed emergency tube thoracostomy or surgical intervention * Hemodynamically unstable * Open and/or infected wounds in the fracture area

Design outcomes

Primary

Measure	Time frame	Description
Pain control	60th minutes.	We use Numeric rating scala.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026