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Volatility and Heterogeneity of Vaccine Sentiments Means Continuous Monitoring is Needed When Measuring Message Effectiveness

The Effect of Optimised Online Advertising on the Uptake of COVID-19 Vaccines in Hong Kong

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05499299
Enrollment
127000
Registered
2022-08-12
Start date
2021-07-01
Completion date
2022-04-01
Last updated
2022-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaccine-Preventable Diseases, Vaccine Refusal

Keywords

Vaccine hesitancy, Google ads, Vaccine messages, Vaccine confidence

Brief summary

The success of vaccination programs often depends on the effectiveness of the vaccine messages, particularly during emergencies such as the COVID-19 pandemic. The current suboptimal uptake of COVID-19 vaccines across many parts of the world highlights the tremendous challenges in overcoming vaccine hesitancy and refusal even in the context of a world-devastating pandemic. The investigators conducted a randomized controlled trial in Hong Kong to evaluate the impact of seven vaccine messages on COVID-19 vaccine uptake (with the government slogan as the control). The participants included 127,000 individuals who googled COVID-19-related information during July-October 2021.

Detailed description

This study aims to evaluate the effectiveness of using the Google advertising platforms on influencing the uptake of COVID-19 vaccines in Hong Kong. When completed, the rich database compiled through this proposed study will provide increased insight into vaccine hesitancy in Hong Kong. Insights from the optimised online advertising trial can aid in providing crucial technical and theoretical support to the relevant health authorities for any potential evidence-based policy intervention in addressing vaccine hesitancy issues or the public's concerns towards vaccines in Hong Kong.

Interventions

BEHAVIORALGoogle ads

Individuals who googled COVID-19 information in Hong Kong were randomized to see one of the seven ads and, if they clicked on the ads, the corresponding vaccine message on our website

Sponsors

The University of Hong Kong
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* General users of Google search in Hong Kong

Exclusion criteria

* None

Design outcomes

Primary

MeasureTime frameDescription
Number of bookings following each message delivery within 6 hours6 hoursThe number of bookings made within X = 6 hours following each message delivery

Secondary

MeasureTime frameDescription
Number of bookings following each message delivery within 3 hours3 hoursThe number of bookings made within X = 3 hours following each message delivery
Number of bookings following each message delivery within 12 hours12 hoursThe number of bookings made within X = 12 hours following each message delivery

Countries

Hong Kong

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026