The Effect of Gallstone Characteristics for the Severity of Gallstone Pancreatitis

The Effect of Gallstone Characteristics for the Severity of Acute Gallstone Pancreatitis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05498961

Enrollment

301

Registered

2022-08-12

Start date

2022-08-10

Completion date

2023-09-24

Last updated

2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Gallstone Pancreatitis

Keywords

Pancreatitis, Gallstone, Severity

Brief summary

The purpose of this study was to determine the effect of gallstone characteristics for the severity of acute gallstone pancreatitis (GSP)

Detailed description

The timing of cholecystectomy is closely related to the severity of acute gallstone pancreatitis (GSP). The effect of gallstone characteristics (including stone size, number, etc.) for the severity of GSP are currently unknown.

Interventions

OTHERGallstone characteristics

stone size, number, the thickness

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Acute gallstone pancreatitis (GSP) patients.

Exclusion criteria

* Pancreatitis with bile duct stones, trauma, drugs, and surgery; * Recurrent gallstone pancreatitis; * Combined with other malignant tumors, such as liver cancer, cholangiocarcinoma, pancreatic cancer, gastric cancer, Hematologic tumor, and lymphoma; * Previous hepatobiliary and pancreatic surgery, Organ transplantation; * Intestinal obstruction or other obstructive diseases; * Chronic pancreatitis or pancreatic duct stones; * Thrombotic disease; * Alcoholic pancreatitis and hyperlipidemia pancreatitis.

Design outcomes

Primary

Measure	Time frame	Description
Number of severity of GSP patients	1 month	Based on the 2012 Atlanta International Consensus, Mild acute pancreatitis (MAP) is defined as no organ failure and no local or systemic complications. Moderate to severe acute pancreatitis (MSAP) refers to patients with organ failure, local complications, or aggravated complications. Severe acute pancreatitis (SAP) is defined as persistent organ failure for more than 48 hours.

Secondary

Measure	Time frame	Description
Modified computed tomography severity index (MCTSI) score	1 month	Without knowing the prognosis, two radiologists with eight and ten years of experience independently scored the severity of GSP through the MCTSI score and reached an agreement through discussion when there was disagreement.
Gallstone size	1 month	The diameter of the stones
Number of stones	1 month	The number of gallstones

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026