Stricture of Pelviureteric Juncture
Conditions
Keywords
PUJS, MRI, Scintigraphy, Polar Vessel
Brief summary
Pyelo-ureteral junction syndrome is the most common urological abnormality in children. Functional MRI has been evaluated several times and has shown good correlation with scintigraphy, but tends to overestimate results. Moreover, those studies included a small number of cases. Its sensitivity to detect crossing polar vessels is limited. The investigators aimed to evaluate, in patients between 0 and 1 year old, the correlation between MRI and scintigraphy differential renal function. The secondary objectives are the evaluation of MRI performances to detect polar vessels; the comparison of surgery times depending on MRI-only realization or MRI and scintigraphy realization.
Interventions
DIAGNOSTIC_TESTFunctional MRI
Anatomical MRI : T2 fiesta, SSFE, HASTE ; 3D T2 ; T1 FAT SAT ; LAVA Functional MRI : T1 FAT SAT with gadolinium
Sponsors
Central Hospital, Nancy, France
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Days to 17 Years
Healthy volunteers
No
Inclusion criteria
* children between 0 and 17 years old * followed for pyelo-ureteral junction syndrome
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MRI and scintigraphy differential renal function correlation | from january 2007 to december 2021 | Evaluation of differential renal function between MRI and scintigraphy in children between 0 and 1 year old ; Pearson correlation coefficient |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| MRI and scintigraphy differential renal function correlation in operated patient | from january 2007 to december 2021 | Evaluation of differential renal function between MRI and scintigraphy in children operated for PUJS; Pearson correlation coefficient |
| Time difference in patient operated for PUJS depending on MRI realisation ou MRI and scintigraphy realisation | from january 2007 to december 2021 | Comparison between the mean time between MRI and surgery, and mean time between MRI, scintigraphy and surgery |
| performance of MRI in detecting polar vessel | from january 2007 to december 2021 | Polar vessel : comparison between MRI results and operatory observation, sensitivity et specificity analysis |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORCharles Mazeaud
CHRU Nancy
Outcome results
None listed