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Vital Pulp Therapy With Different Materials for Young Permanent Teeth

Clinical Evaluation of Different Treatment Modalities for Vital Pulp of Immature Permanent Molars

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05498337
Enrollment
100
Registered
2022-08-12
Start date
2022-09-01
Completion date
2024-04-01
Last updated
2025-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vital Pulp Therapy

Keywords

Alpexogenesis, MTA, Calcium hydroxide, Diode Laser

Brief summary

This study will be conducted to: Evaluate clinically and radiographically apexogenesis in immature permanent molars using: 1. Calcium Hydroxide. 2. MTA. 3. Laser. 4. Laser combined with MTA.

Detailed description

Calcium Hydroxide has been the most commonly utilized pulpotomy agent for vital pulp therapy. It is the earliest medicament employed in pulpotomy that possesses the ability to stimulate tertiary dentinogenesis. This is attributed to its high alkalinity after mixing with water. Calcium hydroxide has a high pH, and its dental use relates chiefly to its ability to stimulate mineralization and also to its antibacterial property. Biocompatibility and sealing ability are the most important properties, which account for optimal healing response in vital pulp therapy. Unlike conventional materials, MTA has low solubility and maintains its physical integrity after placement. It has several desirable characteristics in terms of biocompatibility, bioactivity, hydrophilicity, radiopacity, sealing ability and low solubility. Diode laser in a young permanent tooth with traumatically exposed pulp has proved to be an effective technique for Pulpotomy in an immature tooth. Therefore, the use of soft-tissue diode lasers can influence the treatment outcome and should be seen as a predicable tool for vital pulp therapy.

Interventions

OTHERcalcium hydroxide

Dental pulp medicament material

OTHERMTA

Dental pulp medicament material

DEVICEDiode Laser

Device used in pulp therapy

Sponsors

Mansoura University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
7 Years to 9 Years
Healthy volunteers
Yes

Inclusion criteria

* Medically free * Vital teeth

Exclusion criteria

* Medically compromised * Chronic abscess * Non-vital teeth

Design outcomes

Primary

MeasureTime frameDescription
Root completionone yearClosure of radiographic apex using Scanora 5.2.6 digital software

Secondary

MeasureTime frameDescription
Root lengthening and thickeningone yearMeasuring the increase in length and width of the root canals using Scanora 5.2.6 digital software

Other

MeasureTime frameDescription
Clinical evaluationone yearAbsence of pain and tenderness to percussion using facial scale

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026