Heart Failure With Preserved Ejection Fraction
Conditions
Keywords
visceral fat area
Brief summary
Study of the prognosis of patients with heart failure with preserved ejection fraction
Detailed description
Obesity is an independent risk factor for heart failure with preserved ejection fraction (HFpEF), however, the impact of visceral fat area (VFA) in patients with HFpEF is unclear. According to established process of patients' selection, a total of 172 patients whose mean age was 72 years were included in this study, and the median follow-up duration was 395.5 days(interquartile range: 207.5 to 535.5 days). All patients were divided into two groups based on the best cut-off value of VFA, and the primary outcome of this study was all-cause death in patients with HFpEF. The aim of this study was to clarify whether VFA has prognostic value in patients with HFpEF by Kaplan-Meier analysis and cox analysis.
Interventions
None listed
Sponsors
Chongqing Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Adult aged \>=18years old; 2. Diagnosed with HFpEF.Diagnostic criteria including: 1）left ventricular ejection fraction ≥50%； 2）with the symptoms and/or signs of heart failure； 3）BNP≥35 pg/mL and/or NTproBNP≥125 pg/mL； 4）at least one additional criterion: relevant structural heart disease(LVH and/or LAE) or diastolic dysfunction
Exclusion criteria
1. Age \<18 years old； 2. LVEF less than 45% at any time; 3. cancer diagnosis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| death | The median follow-up time of 395.5 days(interquartile range: 207.5 to 535.5 days) | all-cause death |
Countries
China
Outcome results
None listed