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The Ultrasonographic Changes of Intercostal Muscles and Diaphragm in Mechanically Ventilated Preterm Neonates

The Ultrasonographic Changes of Intercostal Muscles and Diaphragm in Mechanically Ventilated Preterm Neonates

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05495763
Enrollment
30
Registered
2022-08-10
Start date
2022-08-31
Completion date
2023-01-31
Last updated
2022-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical Ventilation Complication

Brief summary

Invasive mechanical ventilation induces ventilator induced diaphragmatic dysfunction particularly when used for long time and Intercostal muscles as well contribute to the important work of respiratory movement by expanding the thorax , and determining the thickness of them would be a useful parameter in evaluating respiratory muscle activity. This study will add the impact of mechanical ventilation on the diaphragm and intercostal muscles in preterm infants using ultrasound.

Interventions

None listed

Sponsors

Noha Saied Ibrahim
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
5 Minutes to 28 Days

Inclusion criteria

1. Preterm infants from 28-36 weeks gestation 2. In need for invasive mechanical ventilation according to work of breathing, oxygen saturation and blood gases .

Exclusion criteria

* 1\) Significant congenital anomalies including cardiac, abdominal or respiratory. 2\) Congenital anomalies involving the diaphragm. 3) Phrenic nerve paralysis. 4) Congenital muscular dystrophies. 5) Major upper or lower airway anomalies. 6) Storage diseases.

Design outcomes

Primary

MeasureTime frameDescription
The impact of mechanical ventilation on diaphragm and intercostal muscles using ultrasound6 monthsUsing Ultrasound to measure Intercostal Muscles thickness and diaphragmatic thickness and excursion for assessing the impact of the mechanical ventilation on muscle power predicting weaning from ventilation.

Countries

Egypt

Contacts

Primary ContactNoha Ibrahim, MB, BCh
Nohasaied2000@gmail.com01064099564

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026