Effects of Moderate Physical Activity on Early Symptoms of Peripheral Diabetic Neuropathy in Type-II Diabetes: A Randomized Clinical Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05491850

Enrollment

Registered

2022-08-08

Start date

2021-10-01

Completion date

2021-12-25

Last updated

2022-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral Diabetic Neuropathy

Keywords

Type 2 diabetes mellitus, moderate physical activity, HbA1c, diabetic neuropathy

Brief summary

This study determines the effects of moderate physical activity on early symptoms of peripheral diabetic neuropathy in type-II diabetes. Most of the literature shows the impact of physical activity to manage/controlling diabetes. Some studies were conducted on animals to study the impact of physical activity on diabetic neuropathy and neurogenesis. There is no study on the impact of physical activity to manage early symptoms of peripheral diabetic neuropathy in patients with type-II diabetes in humans. This study finds the impact of moderate physical activity to manage early symptoms of peripheral diabetic neuropathy in patients with type-II diabetes in humans.

Interventions

OTHERModerate Physical Activity for Peripheral Diabetic Neuropathy

Moderate physical activity can increase movement and heart rate are particularly important for people suffering with peripheral neuropathy. Physical activity can improve blood circulation, which strengthens nerve tissues by increasing the flow of oxygen.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

35 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Patients with Type-II Diabetes * Diagnosed cases of Peripheral Diabetic Neuropathy * Peripheral Diabetic Neuropathy Stage 1 & 2 * Numbness or reduced ability to feel pain or temperature changes. * Tingling or burning sensation. * Sharp pains or cramps. * Increased sensitivity to touch * Males and females * Age: 35-65 * HbA1c above 6.5 * Mild activity level on IPAQ-7 (\< 150min/per week) * Berg Balance Scale score (\< 45)

Exclusion criteria

* Cardiac Issues * Any neurological issue * Lower limb deformity * Acute injury * Hip and Knee OA * Patients with walking difficulty * Diabetic foot

Design outcomes

Primary

Measure	Time frame	Description
Effect of moderate physical activity on early symptoms of peripheral diabetic neuropathy in type-II diabetes	2 Months	Research Hypothesis

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026