Stroke, Stroke Hemorrhagic, Stroke, Ischemic
Conditions
Brief summary
The Bio-Repository of DNA in Stroke (BRAINS) recruits all subtypes of stroke as well as controls from two different continents, Europe and Asia. Subjects recruited from the United Kingdom (UK) will include stroke patients of European ancestry as well as British South Asians. Stroke subjects from South Asia will be recruited from India and Sri Lanka. Subjects are also recruited in Qatar. South Asian cases will also have control subjects recruited.
Interventions
None listed
Sponsors
Royal Holloway University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Cases Inclusion Criteria: * Patients should be aged \> 18 years at the time of enrolment. * Diagnosis of haemorrhagic or ischemic stroke using World Health Organization guidelines confirmed by clinical examination and imaging (CT or MRI). * All patients with cerebral arteriovascular malformations and aneurysms. * South Asian or Caucasian ethnic backgrounds. * Patient or relative written informed consent.
Exclusion criteria
* Unable to provide consent themselves or through surrogate. * Stroke not defined on CT or MRI. Controls Inclusion Criteria: * Patients should be aged \> 18 years at the time of enrolment. * No previous history of stroke. * able to provide written consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DNA repository of highly phenotyped stroke patients | 5 years |
| Identify novel gene loci associated with different types of stroke | 5 years |
Countries
United Kingdom
Contacts
Primary ContactPankaj Sharma, MD PhD
Outcome results
None listed