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A Big Data-based Cohort Study for Cataract Patients

A Big Data-based Cohort Study for Cataract Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05491798
Enrollment
1000
Registered
2022-08-08
Start date
2020-07-01
Completion date
2025-06-30
Last updated
2024-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract, Retina Disorder

Keywords

Cataract, Postoperative prediction, Image enhancement, Retina disorder

Brief summary

Cataract is an important cause of blindness and visual impairment worldwide. At present, the only effective treatment method is surgery. The visual function of most patients can be significantly improved after surgery, but there are still 5-20% of patients whose visual function cannot be improved after surgery. Previous studies have found that the surgical complications and postoperative visual function of cataract patients are closely related to the condition of the fundus, but the current fundus camera cannot perform clear fundus imaging of cataract patients, and the existing potential visual inspections, such as retinal visual inspection, are also inaccurate. Predict postoperative visual acuity. Therefore, there is an urgent need for a reliable postoperative effect prediction system for cataract patients to provide reference for both ophthalmologists and patients. This study intends to collect patient medical record information and traditional/ultra-wide fundus photos and other multi-modal data. Firstly, this study will use artificial intelligence technology to enhance fundus photos of cataract patients to obtain clearer fundus photos. Then this study will use both medical record information and traditional/ultra-wide fundus photographs to predict postoperative vision and visual function of cataract patients.

Interventions

None listed

Sponsors

Sun Yat-sen University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Candidates for cataract surgery (phacoemulsification and intraocular lens implantation) within a week.

Exclusion criteria

* Unwilling or unable to receive fundus photography

Design outcomes

Primary

MeasureTime frameDescription
Change of best corrected visual acuityBaseline and 1 week after surgeryChange of best corrected visual acuity from baseline to 1 week after surgery
Accuracy for detection of retinal disorders1 week after surgeryAccuracy for detection of retinal disorders using enhanced fundus images

Countries

China

Contacts

Primary ContactHaotian Lin, M.D., Ph.D.
linht5@mail.sysu.edu.cn8613802793086

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026