Smoking, Smoking Behaviors, Smoking Cessation, Stress Reaction
Conditions
Brief summary
The purpose of this study is to examine racial differences in smoking behaviors and stress responses between African American and white male smokers.
Detailed description
Cigarette smoking is a leading cause of morbidity and mortality from lung cancer among adults in the US. Stress relief and smoking cessation is the best preventive strategy for reducing lung cancer risk and addressing racial disparities in outcomes. Despite this, racial differences are found among those that make quit attempts. Stress has been found to be related to smoking initiation, maintenance, and relapse. Yet, differences in stress responses have not been examined between African American and white smokers. Therefore, this study will examine racial differences in stress responses and smoking behaviors between African American and white male smokers
Interventions
None listed
Sponsors
Virginia Commonwealth University
City of Hope Medical Center
Medical University of South Carolina
National Cancer Institute (NCI)
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* African American and white males * Between the ages of 18-75 years old * Smoke at least 5 to 10 cigarettes per day
Exclusion criteria
* Smokers who have a serious cognitive disorder * Have a personal history of lung cancer * Personal history of usage of illicit drug and alcohol abuse * Enrollment in a smoking cessation treatment program during the past 6 months * Current use of a nicotine replacement therapy * Have any positive responses on the Mini International Neuropsychiatric Interview (MINI) screener
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Examining racial differences in acute stress responses | Within 1 month following baseline | Examine racial differences in acute stress responses using a validated psychological stress challenge called the Trier Social Stress Test (TSST) |
| Examining changes in daily cortisol patterns according to race | Baseline, 4- and 8 weeks post Trier Social Stress Test laboratory visit | Examine racial differences in daily diurnal cortisol slopes to evaluate hypothalamic-pituitary-adrenal-axis dysregulation and acute stress |
| Examine changes in stress responses and smoking behaviors as it relates to social determinant factors | Baseline, 4- and 8-weeks post Trier Social Stress Test laboratory visit | Patients will be administered a survey using validated measures to examine socioeconomic, structural, and psychosocial stressors that impact daily stress and smoking behaviors |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORVanessa Sheppard, PhD
Virginia Commonwealth University
Outcome results
None listed