Gestational Diabetes
Conditions
Brief summary
In the current literature, there are not enough studies related to the use of uterine artery Doppler indices in the second trimester for the prediction of GDM. Considering that it may be useful in the prediction of GDM in low-risk patient groups for GDM, it was found useful to consider uterine artery Doppler analysis within the scope of this study.In this study, the investigators aimed to assess the value of second-trimester uterine artery Doppler analysis in the prediction of GDM in a low- risk population.
Detailed description
This retrospective research was conducted between June 2020 and December 2021 at the Perinatology Clinic of Haseki Training and Research Hospital. Maternal age between 18 and 42 years and gestational age between 18 and 23 weeks were the inclusion criteria.Pregnant women's computerized records were used to compare the relevant data of women diagnosed with gestational diabetes and women with normal glucose tolerance . Transabdominal ultrasonography was performed for anatomical scanning, and the uterine artery Doppler was obtained using ultrasonographic devices with a 2.0-7.0 megahertz convex probe. The uterine artery waveforms were obtained using pulsed-wave Doppler with an insonation angle of 30° and a peak systolic velocity greater than 60 cm/s. Three identical waveforms were obtained consecutively on each side. In addition to recording the presence or absence of notching, the mean uterine artery pulsatility index (UAPI) was also obtained. Abnormal uterine artery Doppler was defined as a mean UAPI greater than the 95th percentile for each gestation.Increased uterine artery pulsatility index and/or diastolic notch in the uterine artery between 18-23 weeks of pregnancy can predict the risk of GDM in pregnant women.
Interventions
OTHERuterine artery doppler at 18-23 weeks of pregnancy
uterine artery doppler at 18-23 weeks of pregnancy
Sponsors
Haseki Training and Research Hospital
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 42 Years
Inclusion criteria
• Pregnant women with or without Gestational Diabetes in low- risk population
Exclusion criteria
* Pregestational Diabetes * Preeclampsia * Intrauterine growth restriction * Chronic Maternal Disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Uterine artery Doppler ultrasonography in gestational diabetes mellitus | Through study completion, an average of 18 months | To investigate and compare uterine artery pulsatility index by Doppler ultrasonography in patients with gestational diabetes mellitus (GDM) and without to non-diabetic controls. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Prediction of GDM with uterine artery pulsatility index cut-offs | Through study completion, an average of 18 months | Cut off values of uterine artery pulsatility index will be estimated to predict GDM |
Countries
Turkey (Türkiye)
Outcome results
None listed