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Comparison of Pain Relief Between High Thoracic Erector Spinae Plane Block and Cervical Epidural Injection

Comparison of Pain Relief Between High Thoracic Erector Spinae Plane Block and Cervical Epidural Injection

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05487326
Enrollment
82
Registered
2022-08-04
Start date
2022-08-07
Completion date
2023-04-30
Last updated
2023-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Chronic

Keywords

Pain, lumbar

Brief summary

The primary endpoint of this study was to identify whether there is a pain improving effect of high thoracic eretor spinae plane block (ESPB) when compared with cervical epidural injection

Detailed description

The erector spinae plane block (ESPB) is a less invasive, safer, and technically easy alternative procedure to conventional neuraxial anesthetic techniques. In contrast to common neuraxial techniques such as paravertebral and epidural injections, the ESPB targets an interfascial plane which is far from the spinal cord, root, and pleura. First applied to thoracic neuropathic pain, currently ESPB is being applied to postoperative pain control and includes variable clinical situations. In the abdomen and thoracic wall, thoracic ESPB can be applied for pain control after cardiac surgery, video-assisted thoracic surgery, laparoscopic cholecystectomy, and thoracotomy. Recently, favorable postoperative pain control after lumbar spinal or lower limb surgeries has been reported with lumbar ESPB. In addition, ESPB has also been used for chronic pain conditions in the upper and lower extremities. To investigate the possible mechanism of action of the ESPB, many previous studies have focused on examining the physical spread of the injected agent. Commonly, contrast dye injections in human cadavers have been utilized to assess the spread level. Physical spread level was determined using various methods including direct dissection or sectioning, computed tomography (CT), thoracoscopic inspection, or magnetic resonance imaging (MRI) with radiocontrast injection. Apart from human cadaver studies, physical spread level has been evaluated in alive patients using a variable volume of local anesthetics mixed with radiocontrast. However, these studies are limited by the small number of included patients.

Interventions

PROCEDUREErector spinae plane block

fascial plane injection guided by ultrasound guidance

cervical epidural injection by fluoroscopy

Sponsors

Keimyung University Dongsan Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* cervical spinal stenosis * cervical intervertebral disc herniation * cervical facet arthropathy * cervical foraminal stenosis

Exclusion criteria

* Allergy to local anesthetics or contrast medium * Pregnancy * Spine deformity * Patients with coagulation abnormality

Design outcomes

Primary

MeasureTime frameDescription
Changes of numerical rating scalebaseline, 10 min after injection, 1wk after injection, 2 wks after injection, 4 wks after injection, 8 wks after injectionChanges of 11-point numerical rating scale (0-10)

Secondary

MeasureTime frameDescription
Changes of neck disability indexbaseline, 8 wks after injectionChanges of back pain funtional scale

Countries

South Korea

Contacts

Primary ContactJi H Hong, Ph.D
swon13@daum.net01046794343
Backup ContactSung W Jung
swon12@daum.net01021064343

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026