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Outcomes of Early Laparoscopic Cholecystectomy in Cases of Acute Cholecystitis

Outcomes of Early Laparoscopic Cholecystectomy in Cases of Acute Cholecystitis

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05484232
Enrollment
50
Registered
2022-08-02
Start date
2022-08-31
Completion date
2023-02-28
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Calculous Cholecystitis

Brief summary

Laparoscopic cholecystectomy is the most common laparoscopic surgery performed in the world. The initial treatment of acute calculus cholecystitis includes GIT rest, intravenous fluid, correction of electrolyte imbalance from repeated vomiting, good analgesia, and intravenous antibiotics. Following this treatment, patients with uncomplicated disease are managed on outpatient basis and are called for elective laparoscopic cholecystectomy after a period of 6-8 weeks. Elective laparoscopic cholecystectomy has become the gold standard for treatment of symptomatic gallstones. However, in the early days, acute cholecystitis was a contraindication of laparoscopic cholecystectomy, and patients with acute cholecystitis were managed conservatively and discharged for re-admission in order to have elective surgery performed for the definitive treatment. Early laparoscopic cholecystectomy, within 72 hours of presentation,has been advocated because of shorter hospital stay, decreased financial costs and reduced readmission rates. Previously cited reasons against early laparoscopic cholecystectomy include the increased technical difficulties, increased risk of conversion to an open procedure (6-35 % in some studies) and increased risks of biliary complications such as bile leaks and common bile duct (CBD) injuries when operating on an inflamed gallbladder with edematous planes and distorted anatomy.

Interventions

PROCEDURELaparoscopic Cholecystectomy

Early laparoscopic cholecystectomy in patients with acute calcular cholecystitis

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Any patient presented by Acute cholecystitis fit for lap cholecystectomy .

Exclusion criteria

* Patients unfit for laparoscopic surgery such as patients with significant medical illness (ASAgrade more 3), pancreatitis and common bile duct stones

Design outcomes

Primary

MeasureTime frameDescription
duration of surgery ,Intraoperativecompare between duration of surgery between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy
percentage of complications6 monthscompare between percentage of complications of surgery between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy
morbidity6 monthscompare morbidity between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy
mortality6 monthscompare mortality between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy

Countries

Egypt

Contacts

Primary Contactsherif A Ahmed, resident
shreif011109@med.sohag.edu.eg01094995035
Backup ContactAhmed e Ahmed, professor

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026