Iris
Conditions
Brief summary
Estimation of vascular endothelial growth factor (VEGF) in iris tissue specimen in primary congenital glaucoma through Immunohistochemistry.
Detailed description
Combined trabeculotomy with mitomycin C will done in infants with primary congenital glaucoma with histopathological examination of the the peripheral iris tissue specimen and vascular endothelial growth factor (VEGF) estimation in iris tissue specimen through Immunohistochemistry. Estimation of vascular endothelial growth factor (VEGF) in iris tissue specimen taking from ocular trauma or congenital cataract used as control.
Interventions
Estimation of VEGF through Immunohistochemistry
Sponsors
Hassan Lotfy Fahmy
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Days to 1 Years
Healthy volunteers
No
Inclusion criteria
* primary congenital glaucoma
Exclusion criteria
* Infants with history of previous surgery. * Secondary glaucoma. * Glaucoma associated with other congenital anomalies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VEGF | 6 month | Estimation of VEGF grade in iris tissue through Immunohistochemistry, The grades is arranged from 0 to 5, with 0 being the lowest level and 5 being the highest level |
Countries
Egypt
Outcome results
None listed