Childhood Cancer, Nutrition Disorders
Conditions
Keywords
children cancer survivors, adiposity, late effects, nutriton, adipokines
Brief summary
NUTRITION CCS is a cross-sectional, descriptive study to assess the relationship between body composition and demographic, socioeconomic status, treatment modalities and blood samples of survivors who were in remission. The study was conducted in the Clinic for childhood cancer survivors. The clinic is attended by patients older than 18 years and was built in 2016 at the St. Anne's Hospital in Brno.
Detailed description
NUTRITION CCS is a cross-sectional, descriptive study to assess the relationship between body composition and demographic, socioeconomic status, treatment modalities and blood samples of survivors who were in remission. Objectives of the study 1. to determine the prevalence (incidence) of nutritional disorders, especially obesity and metabolic syndrome, in cured paediatric cancer patients in adulthood; 2. to investigate the role of adipokines in the development of cardiometabolic complications in this group of patients; 3. to determine whether targeted dietary and lifestyle interventions can lead to improvements in nutritional status and subjectively perceived quality of life of treated paediatric cancer patients in adulthood and objectively assessed cardiometabolic risk
Interventions
OTHERnutritional interventions
Nutritional intervention will be initiated in patients at risk of overweight and obesity. A targeted nutritional intervention will be carried out, which will include consultation on dietary habits and physical activity as determined by diet and physical activity records. Consultations will be aimed at improving lifestyle and maintaining an adequate body weight.
Sponsors
St. Anne's University Hospital Brno, Czech Republic
Masaryk University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
* Patients after treatment from childhood and adolescent cancers. * The subject is male or female, aged 18 - 64 years
Exclusion criteria
* Patients with acute cancer therapy * Pregnant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Define the relationship between the levels of adipokines and cardiometabolic diseases. | through study completion, an average of 1 year | Define the relationship between the levels of selected adipokines and the risk of selected chronic diseases, specifically cardiometabolic diseases. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Determine the prevalence of hight body fat and decreased skeletal muscle. | through study completion, an average of 1 year | Determine the number of patients with a high body fat percentage. In these patients, monitor the responses of selected adipokine levels to targeted nutritional intervention leading to fat mass reduction. |
Countries
Czechia
Contacts
Primary ContactTomáš Kepák, MUDr.
Backup ContactLucie Štrublová, Mgr.
Outcome results
None listed