Hemodynamic Instability, Hypotension During Surgery
Conditions
Brief summary
In this study investigators will explore the association between intraoperative arterial hypotension and cerebral oxygen saturation in patients scheduled for major abdominal surgery. Investigators will assign patients to control or interventional group. In this last group arterial hypotension will be avoided based on a HPI (Hypotension Predictive Index) protocol. In the control group arterial hypotension will be promptly treated according to hemodynamic variables.
Interventions
DEVICEHPI
based on HPI values, clinicians will administer drugs or fluids in order to avoid arterial hypotension
Sponsors
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients scheduled for abominal surgery
Exclusion criteria
* Emergency surgery * end-stage renal disease * pregnancy * obesity * atrial fibrillation * previous cerebral ischaemia * central nervous system disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cerebral tissue oximetry | immediately after surgery | the difference among the two groups of the percentage value of the median value of Cerebral Oxygen Saturation measured by the near-nfrared spectroscopic technology (Foresight sensor) |
Countries
Italy
Contacts
PRINCIPAL_INVESTIGATORAndrea Russo, MD
Fondazione Policlinico Universitario Agostino Gemelli
Outcome results
None listed