Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay
Conditions
Brief summary
This exploratory study used a pre-post test design. The supervised rehabilitation program was performed three times a week for 8 weeks (two sessions at a rehabilitation gym and one pool session). Outcome measures included Ottawa sitting scale, 30-Second Chair Stand test, Berg Balance Scale, 10-Meter Walk Test, 6-minute Walk Test, modified Activities-specific Balance Confidence Scale and SARA scale. 10 participants will complete the training program. They will be evaluated at baseline, at week 4 (miway) and after the program.
Interventions
OTHERTraining program
8-week rehabilitation program aimed at increasing trunk and lower limb motor control on balance and walking abilities, and accomplishment of activities of daily living.
Sponsors
Muscular Dystrophy Canada
Élise Duchesne
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Genetically confirmed ARSACS diagnosis; walker (indoor walking abilities with or without walking aids); ability to walk 10 meters; ability to provide informed consent
Exclusion criteria
* Having other medical diagnosis causing physical limitations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the Scale for the assessement and rating of ataxia (SARA) | Baseline, week 4, week 8 | Measured with the Scale for the assessement and rating of ataxia (SARA), score range 0-40, higher score indicates higer ataxia severity |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in the number of sit-to-stand performed in 30 seconds | Baseline, week 4, week 8 | Number of complete sit-to-stand performed in 30 seconds without the help of arms |
| Change in the balance confidence | Baseline, week 4, week 8 | Measured with the modified Activities-specific Balance Confidence (ABC) Scale, score range 0-100, 0 indicates no confidence and 100 is full confidence. |
| Change in walking speed | Baseline, week 4, week 8 | Change in the walking speed, measured with the time to walk 10 meters at comfortable and maximum speed |
| Change in sitting balance | Baseline, week 4, week 8 | Measured with the Ottawa sitting scale, score range 0-40, a higher score indicates a better outcome. |
| Change in the level of independence to perform daily living activities | Baseline, week 4, week 8 | Measured with the Barthel Index, score range 0-100, a higher score indicates a higher level of independence. |
| Change in balance | Baseline, week 4, week 8 | Measured with the Berg Balance Scale, score range 0-56, a higher score indicates better balance. |
Countries
Canada
Outcome results
None listed