Myopia
Conditions
Brief summary
Both orthokeratology and atropine eye drops are effective methods for myopia control, but few studies have compared them all together simultaneously. Therefore, the primary aim of the present study was to compare the effect of orthokeratology versus low-dose (0.01% and 0.02%) atropine on the control of myopia progression.
Interventions
DRUGlow-dose atropine eye drops
low-dose atropine eye drops
DEVICEorthokeratology
orthokeratology, ortho-K lenses
Sponsors
Evidence Based Cataract Study Group
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
8 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
Best corrected visual acuity less then 0.00 log MAR (minimum angle of resolution) units Cycloplegic SER of - 1.0 D or less in both eyes. An inter-eye cycloplegic SER difference of 1.00 D or more.
Exclusion criteria
Children with cycloplegic cylinder refraction of more than + 1.00 D or less than - 1.00 D. History of binocular vision problems, including strabismus. History of known ocular disorders, including media opacities, macular dysgenesis, optic nerve hypoplasia, perinatal brain injury, buphthalmos, and retinopathy of prematurity. History of medication use that might have affected the refractive results. Systemic or developmental problems that might have hindered refractive development.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Progression of myopia | 1 year | The change of myopia (Ds) |
| Progression of axial length | 1 year | The change of axial length (mm) |
Countries
China
Contacts
Primary ContactPeng Zhou, M.D.
Outcome results
None listed