Skip to content

Oxygen Consumption in Post-stroke Patients During Various Walking Activities Compared to Healthy Controls

Oxygen Consumption in Post-stroke Patients During Various Walking Activities Compared to Healthy Controls

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05477238
Acronym
STROXCO
Enrollment
60
Registered
2022-07-28
Start date
2022-09-07
Completion date
2023-06-26
Last updated
2023-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular Accident

Keywords

Stroke, Oxygen consumption, physical activity

Brief summary

Stroke is major public health issue. The investigators recommend post-stroke patients to practice physical activity. Nevertheless, the recommendations are not widely respected due to the intensity of exercises. Oxygen consumption is a parameter to assess the intensity of physical activity. in this sense, we want to measure the oxygen consumption during various walking tasks compared to healthy controls.

Detailed description

Stroke is defined as an interruption of blood circulation in the brain. The treatments are in first time medical in emergency. Then, the patient will start his rehabilitation with several contributors. At this time, it will recommend physical activity to patients. Regardless of the all benefits of physical activity, it will help patient to avoid a second stroke. The investigators have the recommendations of the high authority of health in physical activity for stroke population. It recommends to practice around 20 to 60 minutes daily of physical activity with moderate effort intensity. Oxygen consumption is a parameter of effort intensity of physical activity measured in ml O2/kg/min. Currently, the investigators have the compendium of physical activity (PA). it allows us to classify PA according to effort intensity. And so, an activity with a moderate effort intensity is an activity between 3 and 5.9 metabolic equivalent task (MET). Note that 1 MET is 3.5 ml/O2/Kg. Nevertheless, this compendium does not correspond to post-stroke individuals. As consequences, Low intensity exercise as described in guidelines might be at a moderate intensity level for stroke survivors. Hence, the investigators want to assess the oxygen consumption of post-stroke individuals during various walking tasks and compare it to healthy controls.

Interventions

PROCEDUREwalking tasks

The experiment will be divided in two sessions. In the first session, the participant/healthy volunteers will do 3 walking tasks (over ground walking/ climbing up, down stairs). In the second session, the participant will walk outside in front of the hospital (walking on a slope, walking down, walking on uneven ground). All those tasks will be done while wearing a gas exchange analyzer, accelerometer and a heart rate meter.

Sponsors

University Hospital, Limoges
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Intervention model description

Monocentric, cross-sectional and comparative study

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Common to both groups: * Age \>=18 years * Able to give consent * Not under guardianship or curatorship * Enrolled in the French social security system Specific to the cerebrovascular accident Group: * Stroke confirmed by brain imaging * Able to walk stairs without human assistance (modified Functional Ambulation Classification \>= 6) Healthy Group Specific: \- Individuals matched to stroke individuals on age sex and BMI.

Exclusion criteria

Cerebrovascular accident group - Severe cognitive impairment (MoCA \< 18) Common to both groups: \- Presence of contraindication to physical activity: unstable diabetes, unstable hypertension, unstable angina, intra-cardiac thrombus.

Design outcomes

Primary

MeasureTime frameDescription
Oxygen consumption measurementDay 1Oxygen consumption by indirect calorimetry (respiratory gas exchange analyzer: Metamax) expressed in mL.min-1.kg-1

Secondary

MeasureTime frameDescription
Walking speed measurementDay 1Average walking speed measured (distance walked/total time) during different travel activities
Cardiac frequency measurementDay 1Average heart rate during activity measured by heart rate meter in bpm
Perception of effortDay 1Perception of effort by the Borg scale during the last minute of the movement activity
Total energy expenditureDay 1Total energy expenditure during each movement activity estimated by an Actigraph GT3X placed at the healthy ankle

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 20, 2026