Metabolic Disease
Conditions
Keywords
self-health management, metabolic diseases, sarcopenia, frailty, intervention
Brief summary
The lifestyle program intervention program focusing on healthy dietary habit and exercise effectively prevents metabolic syndrome, sarcopenia or frailty. Thus, the purpose of this study was to assess the efficacy of intervention program on metabolic syndrome subjects in Taiwan.
Detailed description
The study is a 2-parallel groups' randomized controlled trial. Participants with metabolic syndrome (three or more risk factors - triglycerides (TG) \>150 mg/dL, systolic blood pressure (SBP) ≥130 mm Hg, diastolic blood pressure (DBP) ≥85 mm Hg, or fasting blood glucose≥100 mg/dL; high-density lipoprotein cholesterol\<50 mg/dL, or waist circumference ≥80 cm) are enrolled. The four community units are randomized to receive a lifestyle intervention (intervention arm) or an education leaflet (control arm). The parameters are obtained from physical examination and biochemical assessments by well-trained case manager at baseline and 4th months. All participants complete a structured questionnaire, including basic information, SOF, physical performance, physical activity, and food-frequency.
Interventions
BEHAVIORALself-management skills and healthy technology APP
self-management skills and healthy technology APP
Sponsors
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan
Chang Gung University of Science and Technology
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
40 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* older adult with age ≥ 40 years * community-dwelling * no hearing and visual acuity difficulties
Exclusion criteria
* Unconscious * Cognitive impairment or dementia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frailty | 4 month follow up | measurement used study of osteoporotic fracture index (SOF). |
| BMI | 4 month follow up | weight and height will be combined to report BMI in kg/m\^2 |
| metabolic syndrome | 4 month follow up | changes in triglycerides, high-density lipoprotein cholesterol, systolic blood pressure, diastolic blood pressure, fasting blood glucose, waist circumference |
| body weight | 4 month follow up | weight in kilograms |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| physical agility and dynamic balance ability | 4 month follow up | Timed-Up and Go and Functional Reach Test |
| short physical performance battery | 4 month follow up | sit-to-stand, standing balance, and gait-speed |
| upper limb muscle strength | 4 month follow up | hand-grip strength |
| static balance ability | 4 month follow up | single-leg standing with the eyes open |
Other
| Measure | Time frame | Description |
|---|---|---|
| Physical activity | 4 month follow up | used International Physical Activity Questionnaire (IPAQ) |
| dietary behaviors | 4 month follow up | intake rate of whole grains, vegetables, fruits, proteins, dairy products, and nuts. |
Countries
Taiwan
Contacts
Primary ContactShu-Hung Chang, Ph.D
Outcome results
None listed