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Dry Eye Under China's Dynamic COVID-zero Strategy

Dry Eye Symptoms of University Students Under China's Dynamic COVID-zero Strategy: A Comparison Between the Epidemic and Non-epidemic Areas

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05476068
Enrollment
1807
Registered
2022-07-27
Start date
2022-03-20
Completion date
2022-05-25
Last updated
2022-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye Symptoms

Keywords

dry eye symptoms, anxiety, depression

Brief summary

To compare the prevalence of dry eye symptoms and to investigate the association of the risk factors with the dry eye symptomatology among university students in the epidemic and non-epidemic areas of China under the COVID-zero strategy.

Detailed description

As the COVID-19 outbreak at the end of 2019 spread around the world, the World Health Organization declared it a public health emergency of international concern on 30th January, and a global pandemic on 1st March. In addition to the threat of coronavirus itself, anti-epidemic measures such as wearing masks, maintaining social distance, prohibiting group gathering, blockade, isolation, curfew, closure, working at home, online learning, etc., have also greatly changed people's daily life dynamics. Unlike the previous regional blockade (city-wide) suspension of school and work, China has shifted to dynamic prevention and control in April 2020, and the basic life and activities in the epidemic area are not restricted. This study aims to compare the prevalence of dry eye symptoms and to investigate the association of the risk factors with dry eye symptoms among college students in the epidemic and non-epidemic areas of China under the dynamic COVID-zero strategy.

Interventions

None listed

Sponsors

Yifeng Yu
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* College students with age ≥18 years * No other medication history in recent 2 weeks; * Have high compliance and are willing to fill in the questionnaire on time

Exclusion criteria

* routinely using artificial tears and Other eye drops; * taking any medication that could interfere with the results of the study; * with any history of eye surgery

Design outcomes

Primary

MeasureTime frameDescription
A score of ocular surface disease index (OSDI)questionnaireDAY 0Ocular surface disease index (OSDI)questionnaire : (1) OSDI: ≤12 (no DED symptoms), 13 ≤ d ≤ 22 (mild DED symptoms), 23 ≤ d ≤ 32 (moderate DED symptoms), and ≥33 (severe DED symptoms).
A score of GAD-7 questionnaireDAY 0GAD-7 questionnaire: (1) 0 \< GAD-7 ≤ 4 (normal), 5 ≤ GAD-7 ≤ 9 (mild anxiety), 10 ≤ GAD-7 ≤ 13 (moderate anxiety), 14 ≤ GAD-7 ≤ 18 (moderate and severe anxiety), and 19 ≤ GAD-7 ≤ 21 (severe anxiety).
A score of PHQ-9 questionnaireDAY 0PHQ-9 questionnaire: (1) 0 \< PHQ-9 ≤ 4 (normal), 5 ≤ GAD-7 ≤ 9 (mild depression), 10 ≤ GAD-7 ≤ 14 (moderate depression), 15 ≤ GAD-7 ≤ 19 (moderate and severe depression), and 20 ≤ GAD-7 ≤ 27 (severe depression).

Secondary

MeasureTime frameDescription
A score of UCLA Loneliness Scale questionnaireDAY 0UCLA Loneliness Scale Questionnaire: (1) UCLA \< 28 (low loneliness), 28 ≤ UCLA ≤ 33 (generally lower), 33 \< UCLA ≤ 39 (intermediate level), 39 \< UCLA ≤ 44 (generally higher), and GAD-7 \> 44 (highly lonely).
Students' increased use of mobile phonesDAY 0Students choose to increase the time of using mobile phones according to options: 0 hours, less than 1 hour, 1-3 hours, 3-5 hours, 5-7 hours, and more than 7 hours
Frequency of student sportsDAY 0Students choose the frequency of sports according to the options, which are: less than once a month, 2-3 times a month, 1-2 times a week, 3-5 times a week, and once a day.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026