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Role of MSCT of Chest in Differentiation Between COPD Patients According to Their Smoking Status

Role of Multislice Computed Tomography (MSCT) Chest in Differentiation Between Chronic Obstructive Pulmonary Disease(COPD) Patients According to Their Smoking Status

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05475977
Enrollment
90
Registered
2022-07-27
Start date
2022-08-31
Completion date
2023-07-31
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient Participation

Brief summary

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality all over the world. Smoking is considered as an important risk factor, but other risk factors are present. Around 30 % of patients with COPD are non-smokers. Cessation of smoking in patients with COPD causes decreases the presence of micronodules and other criteria of CT chest. In last few years, some researchers reported that cessation of smoking raise the apparent extent of emphysema. The cause is not obvious, but this paradoxical fall in lung density is thaught to be resulting from decrease in inflammation after smoking cessation. CT chest criteria of COPD in active smokers, non-smokers and ex-smokers seem to be different. So, comparison between CT chest Criteria of COPD in smokers, ex-smokers and non-smokers will be searched in this study to detect the role of multislice computed tomography (MSCT) chest in differentiation between COPD patients according to their smoking status.

Detailed description

Basic ethical principles of medical research; beneficence (do well), non-maleficence (do no harm), respect and distributive justice were implemented. The study will be carried out in accordance with the Declaration of Helsinki and the principles of good clinical practice.

Interventions

DIAGNOSTIC_TESTMSCT chest

Multi slice Computed Tomography of the chest

Sponsors

Somaia Ahmad AbdAllah Ahmad
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. All patients with chronic obstructive Pulmonary Disease. 2. Patients above 18 years.

Exclusion criteria

1. Patients with unclear smoking history. 2. Patients with active pneumonia. 3. Patients with acute COPD exacerbation.

Design outcomes

Primary

MeasureTime frameDescription
Number of participants with criteria of severe COPD18 monthsCriteria of severe COPD include emphysematous bullae, thick bronchial walls.

Contacts

Primary ContactSomaia Ahmad AbdAllah Ahmad, M.B.B.Ch
somayaahmad64@gmail.com01024833938

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026