Atrial High Rate Episode, Cardiac Implantable Electronic Device
Conditions
Brief summary
This study is sought to investigate any predictors including biomarkers for atrial high rate episodes (AHRE) occurrence in patients without prior history of atrial tachyarrhythmias receiving cardiac implantable electronic device (CIED).
Detailed description
Atrial high rate episodes (AHRE) are noticed up to 70% in patients receiving cardiac implantable electronic device (CIED) even in the absence of prior history of atrial tachyarrhythmias. AHRE is clinically important because it is considered to be associated with clinical atrial fibrillation, stroke, mortality, and heart failure hospitalization. Therefore, predictors of AHRE might be useful for early detection of AHRE susceptable CIED recipients. Biomarkers as well as clinical characteristics will be analyzed.
Interventions
DEVICEimplantable cardiac electronic device recipients
implantable cardiac electronic device recipients for any clinical indication
Sponsors
Pusan National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients receiving cardiac implantable electronic device
Exclusion criteria
* patients who disagree for blood sampling to analyze not commonly used clinical biomarkers * patients not followed-up at least 12 months after implanting device
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurrence of atrial high rate episode | 12 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Factors predicting the occurrence of atrial high rate episode | 12 months | factors including biomarkers such as FGF-23 and soluble ST-2, and single nucleotide polymorphism |
Countries
South Korea
Contacts
Primary ContactJinhee Ahn, MD
Outcome results
None listed