Hearing Loss, Idiopathic Sudden Sensorineural, Hearing Loss, Sudden, SSNHL(Sudden Sensory Neural Hearing Loss), Sudden Hearing Loss
Conditions
Keywords
Hearing Loss, Hearing Loss, sudden, SSNHL, Sudden sensorineural hearing loss, sudden sensory neural hearing loss
Brief summary
This study is to build a cohort of sudden sensorineural hearing loss (SSNHL) patients. When the patient visited the Department of otolaryngology clinic for hearing loss, we can diagnose the SSNHL following the result of pure tone audiometry and the history of the patient. The cohort is a system that tracks the hearing recovery status, timing, and degree of recovery of patients who received cocktail therapy with or without high-dose steroids, vasodilators, antiviral agents, and intratympanic steroid injections, satellite ganglion block, and hyperbaric oxygen therapy.
Interventions
None listed
Sponsors
Wonju Severance Christian Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients over 20 years of age * A patient who visited Wonju Severance Christian Hospital, Department of Otolaryngology and was diagnosed with sudden hearing loss as it was confirmed that hearing loss of 30dBHL or more occurred within 3 days at three consecutive frequencies in a pure tone audiometry test. * Those who have fully explained the purpose and content of the study and voluntarily agreed to the written consent
Exclusion criteria
* If the patients do not want to or do not fill out the consent form * If treatment is started for sudden hearing loss, but the possibility of other inner ear diseases including Meniere's disease is suspected due to repeated hearing loss, repeated recovery, dizziness, tinnitus, etc. * Other cases where it is judged difficult to carry out the clinical trial due to the judgment of the person in charge of the above clinical trial
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hearing outcome 3 weeks - PTA | 3 weeks PTA | Hearing change status near 3 weaks after treatment start measured by pure tone audiometry |
| Hearing outcome 3 months - PTA | 3 month PTA | Hearing change status near 3 months after treatment start measured by pure tone audiometry |
| Hearing outcome 6 months - PTA | 6 months PTA | Hearing change status near 6 months after treatment start measured by pure tone audiometry, which is final. |
| Hearing outcome 1 week - PTA | 1 week PTA | Hearing change status near 1 weak after treatment start measured by pure tone audiometry1 |
| Hearing outcome 2 months - PTA | 2 month PTA | Hearing change status near 3 weaks after treatment start measured by pure tone audiometry |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Electrolytes and chemistries after high dose steroid therapy | 5 days electrolytes and chemistries | The results of blood tests of electrolytes and chemistries at 5 days after treatment start. (Na, K, Cl, CO2, BUN, Cr, Glucose, Amylase, Total protein, Albumin, AST, ALT, ALP, r-GT, Total Bilirubin) |
Other
| Measure | Time frame | Description |
|---|---|---|
| Internal Acoustic canal MRI | MRI | The baseline studies of internal acoustic canal MRI results of SSNHL patients. |
Countries
South Korea
Contacts
Primary ContactTae Hoon Kong, MD, PhD
Outcome results
None listed