AIS
Conditions
Brief summary
Early recanalization is a major prognostic factor in vascular accidents ischemic brain injury (AIC). The acute phase therapies of AIC aim to recanalization by intravenous thrombolysis and/or mechanical thrombectomy. Recanalization is identified immediately during thrombectomy by per-procedural arteriography. For the thrombolysis, only a performed MRI will validate the recanalization. This proof of concept study aims to identify an Electro-Encephalographic biomarker (EEG) of the recanalization in real time, the EEG being easy to set up. This biomarker will be sought during recanalization certified by thrombectomy in order to identify the window time for which the biomarker must be sought on the EEG. During this study, the identified EEG biomarker can be used to validate the recanalization during the intravenous thrombolysis in future studies
Interventions
PROCEDUREPlacement of the EGG
Placement of the EGG before the beginning of the thrombectomy
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Patient over 18 years old * Presenting a cerebral infarction with proximal occlusion of the sylvian artery requiring thrombectomy * No objection to participation in the study
Exclusion criteria
* Pregnant or breastfeeding women * Patient benefiting from legal protection * Absence of affiliation to a social protection scheme * Recent cranial surgery not allowing the installation of a scalp EEG
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| IElectro-Encephalographic (EEG) marker of recanalization | inclusion visit | dentification of an Electro-Encephalographic (EEG) marker of recanalization in patients with cerebral infarction with proximal occlusion of the sylvian artery and recanalized by mechanical thrombectomy |
Countries
France
Outcome results
None listed