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Swallowing Evaluation in VF Immobility

Evaluation of Swallowing in Patients With Vocal Folds Immobility

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05473169
Enrollment
40
Registered
2022-07-25
Start date
2022-07-31
Completion date
2023-08-31
Last updated
2022-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Swallowing Disorder

Brief summary

Vocal fold immobility (VFI) often results in significant problems with dysphonia, dysphagia, and decreased cough strength. As one element of the dysphagia potentially associated with vocal fold immobility, aspiration may create significant morbidity for these patients. An estimated 38% to 53% of patients with untreated VFI have swallowing difficulties with aspiration. Vocal fold immobility has important implication on the laryngeal airway protection during respiration, phonation and swallowing. It is the most common neurological laryngeal disorder. The immobility may be caused by neck and thoracic surgery. which can impair the innervation of the pharynx, upper esophageal sphincter (U.E.S) and proximal esophagus but may also be due to malignancy,trauma, Intracranial causes,or may be idiopathic

Detailed description

Besides the voice alteration, the lesion that causes of vocal fold immobility should also affect the pharyngeal phase of swallowing. It was suggested that dysphagia in patient with vocal fold immobility has multifactor causes ; including limited airway protection and decrease laryngopharyngeal sensation based on the finding of the flexible endoscopy. Another study revealed that pharyngeal phase abnormalities such as delayed initiation of swallowing, reduced laryngeal elevation, and reduced upper esophageal sphincter (UES) opening were found in video fluoroscopic swallowing studies (VFSS). Several studies on the swallowing difficulties of patient with vocal fold immobility has been performed and reported that nearly 56% of these patients immobility have swallowing dysfunction.

Interventions

Swallowing assessment

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

1. Age:above 18. 2. Gender:both sexes will be included in the study.

Exclusion criteria

1. patients with structural abnormalities of oral cavity, pharynx or larynx. 2. previous vocal fold injection or voice therapy. 3. other causes of dysphagia: esophageal cancer or spasm , gastric cancer, cancer larynx,or radio therapy . 4. . Patients with history of heart burn , acid regurgitation , 5. other neurological disease ,stroke, hypothyroidism or dyspnea.

Design outcomes

Primary

MeasureTime frameDescription
To calculate the incidence of swallowing dysfunction in people with vocal fold immobilityBaselineIncidence of swallowing dysfunction in patients with vocal fold immobility will be determined by the Statistical Package for the Social Sciences (SPPS) after the diagnosis of swallowing dysfunction by fiberoptic endoscopic evaluation of swallowing (FEES) and videofluoroscopic swallow study (VFSS)

Secondary

MeasureTime frameDescription
Measure the frequency of each swallowing phase which will be affected in vocal fold immobility patientsBaselineTo detect which swallowing phase is causing the dysfunction by using Statistical Package for the Social Sciences (SPSS) program

Contacts

Primary ContactMohamed Zakaria Ahmed Elbakry, Resident
mohamedelbakry970@gmail.com01101941217
Backup ContactEman Sayed
eshh2003@yahoo.com01004082014

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026