Second-trimester TOP : a Retrospective Study Comparing Complications at 12-14 vs 14-16 Weeks of Gestation

Second-trimester Termination of Pregnancy: A Retrospective Study Comparing Complications Related to Termination of Pregnancy at 12-14 Weeks' Gestation Versus 14-16 Weeks' Gestation

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05469594

Enrollment

122

Registered

2022-07-21

Start date

2010-01-31

Completion date

2021-10-31

Last updated

2022-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abortion in First Trimester, Abortion, Second Trimester

Keywords

complications

Brief summary

In France, the recently adopted law relating to the legal time limit for access to voluntary interruption of pregnancy has set a threshold of the term at which it can be performed up to 16 weeks of gestation. This single-centre study conduced at the Nancy Maternity Hospital is based on a retrospective cohort of all patients who underwent a medical termination of pregnancy between January 2010 and October 2021. The main objective is to evaluate the complications according to the term of the termination of pregnancy between two groups : \[12-14\] vs \[14-16\] weeks of gestation. The secondary objective is the distribution of these complications between the two groups. Pregnancy termination can be performed in two methods, either by medical method with mifepristone and misoprostol, or by surgical method by dilation and evacuation. Complications identified are haemorrhage, infection, retained product of trophoblast, uterine rupture and abortion induction failure. The hypothesis is the concomitant increase in complications with the term of the termination of pregnancy.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* termination of pregnancy for a medical reason * between 12 and 16 weeks of gestation * singleton pregnancy

Exclusion criteria

* multiple pregnancy * abortion occurred before the induction of termination of pregnancy

Design outcomes

Primary

Measure	Time frame	Description
complications	Day 0	hemorrhage, infection, retained product of conception, failure, uterine rupture

Secondary

Measure	Time frame	Description
repartition of all complications	Day 0	repartition of all complications between groups

Outcome results