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Aerosol Generation in Dental Clinics

Mitigating Effect of Bioaerosols During Orthodontic Procedures: a Randomized Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05468099
Enrollment
70
Registered
2022-07-21
Start date
2022-03-29
Completion date
2024-07-31
Last updated
2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentist-Patient Transmission, Occupational Exposure, Risk Reduction

Keywords

aerosol, bioaerosol, dentistry, orthodontics, saliva, nose

Brief summary

The study examines 4 different methods to reduce dental bioaerosol spread in orthodontic procedures.

Detailed description

We aim to examine 4 different methods to reduce dental aerosol spread during orthodontic procedures. These methods are: 1) high-volume evacuator, 2) high-volume evacuator and saliva ejector 3) Local Exhaust System 4) disinfection with povidone-iodine nasal swabs and chlorhexidine mouthwash.

Interventions

OTHERChlorhexidine mouthwash and Povidone-Iodine

Chlorhexidine mouth rinse which participants use for 20 seconds before procedure. Moreover, Povidone-Iodine nasal swabs are used to disinfect nostrils

DEVICEHigh volume evacuator

High volume evacuator held by assistant to capture dental spray

DEVICEHigh volume evactuator and saliva ejector

High volume evacuator and saliva ejector held by assistant to capture dental spray

DEVICELocal Exhaust System

Local exhaust system hovers above patient head to capture dental spray

Sponsors

University of Alberta
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Masking description

Each participant and operator know the model which was assigned to them. The research assistant conducting the analysis is not able to identify the samples until analysis time.

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Orthodontic debonding being performed * Acceptance to participate in the study and provide required saliva and nasal samples

Exclusion criteria

* Refusal to participate * Refusal to provide saliva/nasal swab samples * Allergy to Chlorhexidine gluconate * Allergy to Povidone-Iodine

Design outcomes

Primary

MeasureTime frameDescription
Particle concentration measurements across the 4 different types of interventionsDuring procedure
Mass concentration measurements across the 4 different types of interventionsDuring procedure
Bioaerosol measurement from the tracked sourcesDuring procedureSources include patient, operator and assistant saliva and nasal secretions, preprocedural ambient air, dental unit waterline

Secondary

MeasureTime frameDescription
Bacterial contamination on the inside surface of the mask of operators and assistantsDuring procedureSources include patient, operator and assistant saliva and nasal secretions, preprocedural ambient air, dental unit waterline

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026