Colonic Polyp
Conditions
Keywords
Colonic Polyp, Gastrointestinal Hemorrhage
Brief summary
Currently, hemorrhage remains the most common postoperative complication in patients with colon polyps, with an incidence of approximately 1.5%. The main reasons for postoperative hemorrhage are: the patient's own condition, the nature of the polyp and the operation. The number of patients treated for colon polyps has increased, postoperative care is confusing, medical resources are wasted, and the time span for postoperative diet recovery is large. However, studies on the effect of postoperative dietary recovery timing on postoperative polyp bleeding are rare.
Interventions
DIETARY_SUPPLEMENTEarly diet opening
Effects of early dietary recovery after colon polypectomy and colonoscopic mucosal resection on postoperative hemorrhage in patients
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age 18-75, no gender restrictions, * Patients with colonic polyps identified by colonoscopy and requiring endoscopic treatment, * Polyp size 0.5cm-2cm, * Patients agreed to enroll and signed a written informed consent, * Adherence is good and agrees to be treated and evaluated as required by the study protocol.
Exclusion criteria
* Patients with contraindications to endoscopic treatment of colonic polyps, including platelets ≤50×109/L, prothrombin time prolonged by 4 seconds or more, and INR≥2.0, * Patients with severe heart, brain, lung, blood system diseases, uremia, connective tissue disease, * Patients requiring treatment with NSAIDs, aspirin, glucocorticoids, or clopidogrel within the first 7 days of the study, * During the course of the study, due to other concomitant/complications, patients who need to use drugs that affect the efficacy of the trial, including various anticoagulants, antiplatelet drugs and hemostatic drugs, * Alcoholics, drug addicts or those with uncontrollable neuropsychiatric diseases and others who are not suitable for participating in the trial, * Pregnant, breastfeeding women, or women in childbearing age who wish to become pregnant, * Patients with malignant tumor of digestive system, * Other circumstances in which the investigator believes that the patient should not participate in this trial
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative bloody stool | up to 2 weeks | Postoperative massive hemorrhage: if the amount of blood in stool exceeds 400ml within 1 hour to 14 days after operation, or the hemoglobin decreases \>2g/dl Ordinary hemorrhage: the amount of blood in stool does not meet the above standards |
Countries
China
Contacts
Primary ContactHuihui Yan, PhD&MD
Outcome results
None listed