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Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema

Comparison of the Effects of Hyaluronidase and Dexamethasone on Reduction of Postoperative Edema in Impacted Wisdom Teeth Surgery

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05466604
Enrollment
60
Registered
2022-07-20
Start date
2019-12-01
Completion date
2022-06-30
Last updated
2022-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edema, Infection, Surgical Site, Pain, Trismus

Keywords

postoperative edema, wisdom teeth, trismus, pain control, wound infection

Brief summary

The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection. For this purpose, 60 participants with symmetrical mandibular wisdom teeth enrolled the present study. All measurements and evaluations were performed before and 1, 2, 3, and 7 days later the operation.

Interventions

DRUGHyaluronidase Injection mesomedica

injection of 150 IU hyaluronidase to perioperative region, submucosally.

DRUGDexamethasone dekort

injection of 8 mg dexamethasone to perioperative region, submucosally.

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* symmetrical mandibular wisdom teeth with bone retention * patients who are signed informed consent and acceptance of study involvement forms

Exclusion criteria

* existence of any systemic disease * existence of any periodical drug intake * existence of difference in operation times of right and left impacted wisdom teeth extractions more than 5 minutes * existence of pregnancy * existence of breastfeeding

Design outcomes

Primary

MeasureTime frameDescription
evaluation of the increase of edema in postoperative 1. day using a measuring tape in hyaluronidase experimental grouppostoperative 1. daypreoperative edema amount was subtracted from edema amount in 1. day in hyaluronidase experimental group
evaluation of the increase of edema in postoperative 2. day using a measuring tape in hyaluronidase experimental grouppostoperative 2. daypreoperative edema amount was subtracted from edema amount in 2. day in hyaluronidase experimental group
evaluation of the increase of edema in postoperative 3. day using a measuring tape in hyaluronidase experimental grouppostoperative 3. daypreoperative edema amount was subtracted from edema amount in 3. day in hyaluronidase experimental group
evaluation of the increase of edema in postoperative 7. day using a measuring tape in hyaluronidase experimental grouppostoperative 7. daypreoperative edema amount was subtracted from edema amount in 7. day in hyaluronidase experimental group
evaluation of the increase of edema in postoperative 1. day using a measuring tape in hyaluronidase control grouppostoperative 1. daypreoperative edema amount was subtracted from edema amount in 1. day in hyaluronidase control group
evaluation of the increase of edema in postoperative 2. day using a measuring tape in hyaluronidase control grouppostoperative 2. daypreoperative edema amount was subtracted from edema amount in 2. day in hyaluronidase control group
evaluation of the increase of edema in postoperative 3. day using a measuring tape in hyaluronidase control grouppostoperative 3. daypreoperative edema amount was subtracted from edema amount in 3. day in hyaluronidase control group
evaluation of the increase of edema in postoperative 7. day using a measuring tape in hyaluronidase control grouppostoperative 7. daypreoperative edema amount was subtracted from edema amount in 7. day in hyaluronidase control group
evaluation of the increase of edema in postoperative 1. day using a measuring tape in dexamethasone experimental grouppostoperative 1. daypreoperative edema amount was subtracted from edema amount in 1. day in dexamethasone experimental group
evaluation of the increase of edema in postoperative 2. day using a measuring tape in dexamethasone experimental grouppostoperative 2. daypreoperative edema amount was subtracted from edema amount in 2. day in dexamethasone experimental group
evaluation of the increase of edema in postoperative 3. day using a measuring tape in dexamethasone experimental grouppostoperative 3. daypreoperative edema amount was subtracted from edema amount in 3. day in dexamethasone experimental group
evaluation of the increase of edema in postoperative 7. day using a measuring tape in dexamethasone experimental grouppostoperative 7. daypreoperative edema amount was subtracted from edema amount in 7. day in dexamethasone experimental group
evaluation of the increase of edema in postoperative 1. day using a measuring tape in dexamethasone control grouppostoperative 1. daypreoperative edema amount was subtracted from edema amount in 1. day in dexamethasone controlgroup
evaluation of the increase of edema in postoperative 2. day using a measuring tape in dexamethasone control grouppostoperative 2. daypreoperative edema amount was subtracted from edema amount in 2. day in dexamethasone controlgroup
evaluation of the increase of edema in postoperative 3. day using a measuring tape in dexamethasone control grouppostoperative 3. daypreoperative edema amount was subtracted from edema amount in 3. day in dexamethasone controlgroup
evaluation of the increase of edema in postoperative 7. day using a measuring tape in dexamethasone control grouppostoperative 7. daypreoperative edema amount was subtracted from edema amount in 7. day in dexamethasone controlgroup
evaluation of the difference in increase amounts of edema between hyaluronidase experimental and hyaluronidase control groups in postoperative 1. day using a measuring tapepostoperative 1. dayedema increase amount of hyaluronidase experimental group was compared with that of hyaluronidase control group in postoperative 1. day
evaluation of the difference in increase amounts of edema between hyaluronidase experimental and hyaluronidase control groups in postoperative 2. day using a measuring tapepostoperative 2. dayedema increase amount of hyaluronidase experimental group was compared with that of hyaluronidase control group in postoperative 2. day
evaluation of the difference in increase amounts of edema between hyaluronidase experimental and hyaluronidase control groups in postoperative 3. day using a measuring tapepostoperative 3. dayedema increase amount of hyaluronidase experimental group was compared with that of hyaluronidase control group in postoperative 3. day
evaluation of the difference in increase amounts of edema between hyaluronidase experimental and hyaluronidase control groups in postoperative 7. day using a measuring tapepostoperative 7. dayedema increase amount of hyaluronidase experimental group was compared with that of hyaluronidase control group in postoperative 7. day
evaluation of the difference in increase amounts of edema between dexamethasone experimental and dexamethasone control groups in postoperative 1. day using a measuring tapepostoperative 1. dayedema increase amount of dexamethasone experimental group was compared with that of dexamethasone control group in postoperative 1. day
evaluation of the difference in increase amounts of edema between dexamethasone experimental and dexamethasone control groups in postoperative 2. day using a measuring tapepostoperative 2. dayedema increase amount of dexamethasone experimental group was compared with that of dexamethasone control group in postoperative 2. day
evaluation of the difference in increase amounts of edema between dexamethasone experimental and dexamethasone control groups in postoperative 3. day using a measuring tapepostoperative 3. dayedema increase amount of dexamethasone experimental group was compared with that of dexamethasone control group in postoperative 3. day
evaluation of the difference in increase amounts of edema between dexamethasone experimental and dexamethasone control groups in postoperative 7. day using a measuring tapepostoperative 7. dayedema increase amount of dexamethasone experimental group was compared with that of dexamethasone control group in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 1. daypostoperative 1. daypain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 1. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 2. daypostoperative 2. daypain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 3. daypostoperative 3. daypain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 3. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 4. daypostoperative 4. daypain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 4. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 5. daypostoperative 5. daypain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 5. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 6. daypostoperative 6. daypain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 6. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase experimental group in postoperative 7. daypostoperative 7. daypain intensity of the patients in hyaluronidase experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 1. daypostoperative 1. daypain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 1. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 2. daypostoperative 2. daypain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 3. daypostoperative 3. daypain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 3. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 4. daypostoperative 4. daypain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 4. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 5. daypostoperative 5. daypain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 5. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 6. daypostoperative 6. daypain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 6. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in hyaluronidase control group in postoperative 7. daypostoperative 7. daypain intensity of the patients in hyaluronidase control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 1. daypostoperative 1. daypain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 1. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 2. daypostoperative 2. daypain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 3. daypostoperative 3. daypain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 3. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 4. daypostoperative 4. daypain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 4. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 5. daypostoperative 5. daypain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 5. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 6. daypostoperative 6. daypain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 6. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone experimental group in postoperative 7. daypostoperative 7. daypain intensity of the patients in dexamethasone experimental group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 7. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 1. daypostoperative 1. daypain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 1. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 2. daypostoperative 2. daypain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 2. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 3. daypostoperative 3. daypain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 3. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 4. daypostoperative 4. daypain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 4. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 5. daypostoperative 5. daypain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 5. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 6. daypostoperative 6. daypain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 6. day
evaluation of the pain using visual analog scale (VAS) and daily count of NSAİ drug intake in dexamethasone control group in postoperative 7. daypostoperative 7. daypain intensity of the patients in dexamethasone control group was assessed using visual analog scale (VAS) and daily count of NSAİ drug intake in postoperative 7. day
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group preoperatively.preoperativeamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group in postoperative 1. day.postoperative 1. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group in postoperative 2. day.postoperative 2. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group in postoperative 3. day.postoperative 3. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase experimental group in postoperative 7. day.postoperative 7. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group preoperatively.preoperativeamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group in postoperative 1. day.postoperative 1. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group in postoperative 2. day.postoperative 2. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group in postoperative 3. day.postoperative 3. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of hyaluronidase control group in postoperative 7. day.postoperative 7. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group preoperatively.preoperativeamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group in postoperative 1. day.postoperative 1. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group in postoperative 2. day.postoperative 2. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group in postoperative 3. day.postoperative 3. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone experimental group in postoperative 7. day.postoperative 7. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group preoperatively.preoperativeamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group in postoperative 1. day.postoperative 1. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group in postoperative 2. day.postoperative 2. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group in postoperative 3. day.postoperative 3. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of trismus using a ruler, which measures the opening between mandibular and maxillary right first incisors of dexamethasone control group in postoperative 7. day.postoperative 7. dayamount of trismus is revealed measuring the distance between the tips of incisal edges of mandibular and maxillary right first incisors using a ruler
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group preoperatively.preoperativeexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group in postoperative 1. day.postoperative 1. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group in postoperative 2. day.postoperative 2. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group in postoperative 3. day.postoperative 3. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase experimental group in postoperative 7. day.postoperative 7. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group preoperatively.preoperativeexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group in postoperative 1. day.postoperative 1. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group in postoperative 2. day.postoperative 2. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group in postoperative 3. day.postoperative 3. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of hyaluronidase control group in postoperative 7. day.postoperative 7. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group preoperatively.preoperativeexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group in postoperative 1. daypostoperative 1. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group in postoperative 2. daypostoperative 2. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group in postoperative 3. daypostoperative 3. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone experimental group in postoperative 7. daypostoperative 7. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group preoperatively.preoperativelyexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group in postoperative 1. daypostoperative 1. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group in postoperative 2. daypostoperative 2. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group in postoperative 3. daypostoperative 3. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.
evaluation of infection in operation site via determination of infection signs in physical examination of dexamethasone control group in postoperative 7. daypostoperative 7. dayexistence of infection signs were determined using physical examination method. if the count of + signs are more than half of total amount of determined signs, the evaluation is accepted as (+) infected.

Countries

Cyprus, Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 5, 2026