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Upper Cervical and Thoracic Chiropractic Adjustment

Effects of Upper Cervical and Thoracic Chiropractic Adjustments on the Autonomic Nervous System and Perceived Stress Response

Status
Suspended
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05465395
Enrollment
40
Registered
2022-07-19
Start date
2021-10-12
Completion date
2023-11-01
Last updated
2023-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress

Keywords

Heart Rate Varability, Autonomic Nervious System, Chiropractic Adjustment

Brief summary

The proposed study examines the differences in how the ANS responds to cervical adjustments in comparison to thoracic adjustments. This study is the continuation of a previous study titled Perceived stress and patterns of autonomic function: a protocol development study. Autonomic tests such as HRV, GSR, and the stress surveys will be the primary method of measurement. CareTaker and Biopac devices will provide continual data collection of ECG (for HRV analysis) and GSR throughout the exam and adjustment. Participant's subjective stress levels will be measured through the use of stress questionnaires including the National Stressful Events Survey Acute Stress Disorder Short Scale, the Hamilton Anxiety Rating Scale, and the Connor-Davidson Resilience Scale. The objective of the study is to determine if the location of a chiropractic adjustment will affect the autonomic nervous system in such a way that PNS or SNS activation increases or decreases after the adjustment. Further, the study will continue to examine how the chiropractic adjustment affects the subjective stress response.

Interventions

PROCEDUREUpper Cervical Adjustemnt

Upper cervical adjustement

PROCEDUREThoracic Adjustemnt

Thoracic adjustment

Sponsors

Life University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Over the age of 19 * In good health * Willing to have blood pressure taken * Willinig to shave a small area of chest hair for placement of a ECG patch * Consent to a physical exam * Consent ot chiropractic evaluationa nd 2 adjustments

Design outcomes

Primary

MeasureTime frameDescription
Hamilton Anxiety Rating ScaleThrough study completion, an average of 1 weekMeasures the severity of anxiety symptoms
NSESSSThrough study completion, an average of 1 weekMeasures PTSD symptoms in people 18 and up.
CD-RISC-25Through study completion, an average of 1 weekMeasure of adaptability
Caretaker Heart Rate VariabilityThrough study completion, an average of 1 weekHRV allows for an understanding of Autonomic (parasympathetic) function, via measuring the interval of R peaks in QRS complexes.
Galvanic Skin ResponseThrough study completion, an average of 1 weekGalvanic Skin response gives a strong measure of Sympathetic response via electrical conductivity of perspiration.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026