Skip to content

The Impact of Patient Safety Incidents on Patients' Quality of Life

The Impact of Patient Safety Incidents on Patients' Quality of Life

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05464771
Enrollment
395346
Registered
2022-07-19
Start date
2018-12-01
Completion date
2021-12-01
Last updated
2022-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Fractures, Knee Fracture

Brief summary

This study estimates the impact of patient safety events on QoL in elective surgery patients using a secondary data set

Detailed description

Background: The burden of patient safety incidents (PSIs) is often characterised by their impact on mortality, morbidity and treatment costs. Few studies have attempted to estimate the impact of PSIs on patients' health-related quality of life (HRQoL) and the studies that have made such estimates primarily focus on a narrow set of incidents. The aim of this paper is to estimate the impact of PSIs on HRQoL of patients undergoing elective surgery in England. Materials and Methods: A unique linked longitudinal data set consisting of Patient Reported Outcome Measures (PROMS) for patients with hip and knee replacements linked to Hospital Episode Statistics (HES) collected between 2013/14 and 2016/17 is examined. Patients with any of nine US Agency for Healthcare Research and Quality (AHRQ) PSI indicators are identified. HRQoL is measured using the general EuroQol five dimensions questionnaire (EQ-5D) before and after surgery. Exploiting the longitudinal structure of the data, exact matching combined with difference in differences to estimate the impact of experiencing a PSI on HRQoL and its individual dimensions, comparing HRQoL improvements after surgery in similar patients with and without a PSI.

Interventions

PROCEDURESurgery for hip and knee replacement

Elective inpatient surgery for hip and knee replacement

Sponsors

Imperial College London
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL

Inclusion criteria

* no

Exclusion criteria

* Patients for which health related quality of life is not observed both before and after surgery.

Design outcomes

Primary

MeasureTime frameDescription
EuroQual - 5 Dimensions (EQ5D)2013-17quality of life

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026