Lumbar Spondylolisthesis
Conditions
Brief summary
This study aims to detect the incidence of spondylolisthesis in patients candidate for Total knee replacement (TKR) and to investigate the effect of TKR on the course of low back pain.
Detailed description
Total Knee Replacement (TKR) is one of the most successful surgeries in modern-day orthopedics, performed mainly to treat end-stage knee osteoarthritis (OA) . degenerative spondylolisthesis is one of the most common causes of low back pain where a spinal vertebra slides from its anatomical position, affecting about 11.5% of the population, furthermore, many elderly patients undergoing TKR usually suffer from spondylolisthesis. Spondylolisthesis with subsequent lumbar spine degenerative disease presents as lower back and radiating pain to the legs at rest or during activity, Spondylolisthesis causes hamstring tightness which is felt as pain at the back of the knee, lumbar radiculopathy of the L3 root nerve could vary from thigh pain to hip and/or knee pain, all of which could be misled as pain due to knee OA . On the other hand, patients having knee OA with a flexion deformity compensate their posture by increasing the lumbar lordosis, if the lumbar spine lost its ability to compensate for the knee deformity, this could aggravate low back pain and enhance further lumbar spine instability and spondylosis . In addition, the persistence of coexisting lumbar spine symptoms after TKA might adversely affect postoperative outcomes in terms of pain and function, even after successful TKA . Chang et al., studied the prevalence and severity of coexisting lumbar spondylosis in terms of radiographic lumbar spine degeneration and lumbar spine symptoms in patients with advanced knee OA undergoing TKR, in their study, 51% of patients undergoing TKR had at least one moderate to severe lumbar spine symptom, and patients with severe radicular pain on the activity before the TKR was likely to demonstrate poor knee function 2 years post-TKR . This is why lumbar spine pathologies should be fully investigated in patients coming for TKR.
Interventions
RADIATIONx-ray
plain radiographs of lower limb anteroposterior and lateral views , lumbar spine plain radiographs (anteroposterior, lateral, lateral in flexion and lateral in extension views )
Sponsors
Assiut University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Inclusion criteria
* primary end-stage knee osteoarthritis.
Exclusion criteria
* secondary inflammatory knee osteoarthritis. * post traumatic knee osteoarthritis. * patients with active infection. * patients with poor general condition. * patients who had previous spinal fixation or fusion surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of lumbar spine spondylolisthesis. | Baseline | showing the incidence and occurrence of Lumbar Spondylolisthesis in patients with severe knee Osteoarthritis which needs Total knee replacement |
| Severity of lumbar spine spondylolisthesis. | Baseline | showing the grades of lumbar spine spondylolisthesis through The Meyerding classification system with grade 1 is the minimum and grade 5 is the maximum which in turn has the worst outcome |
| occurence of lumbar spine spondylolishtesis Occurrence of lumbar spine spondylolisthesis | Baseline | Showing the occurrence of lumbar spine spondylolisthesis in patients with severe osteoarthritis which needs total knee replacement |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in characters of low back pain over the postoperative period. | 6 months follow up | Recording the changes of the backpain after Total knee replacement using Oswestry disability index scale which is 0 is the minimum value and 100 is the maximum value which in turn presents with the worst outcome |
| Spine radiological features. | Baseline | Recording the radiological features of Lumber spine through plain xrays of to evaluate the presence of Spondylolisthesis |
| Knee radiological and alignment features. | Baseline | Recording the radiological features of knee through plain xrays of to measure the hip knee ankle angle |
Contacts
Primary ContactMario Sameh Wadie, physician
Outcome results
None listed