IgG4-related Sclerosing Cholangitis, Primary Sclerosing Cholangitis
Conditions
Brief summary
The investigators aimed to collect demographic features and clinical outcomes in patients diagnosed with PSC and IgG4-SC by utilizing participants database from multiple medical centers across Mainland China. Cross-sectional studies will focus on characterizing clinical presentations and validating diagnostic and prognostic models on Chinese PSC and IgG4-SC patients.
Interventions
OTHEROnly observation
No intervention is needed.
Sponsors
RenJi Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Age above 18 years old, * Male or Female, * Patients admitted in our medical centers which met the PSC criteria according to The European Association for the Study of the Liver Clinical Practice Guidelines Management of cholestatic liver diseases in 2009; or patients diagnosed with IgG4-SC which met initially using the Japan Pancreas Society criteria and confirmed using HISORt criteria.
Exclusion criteria
* Female subjects who is pregnant, breastfeeding or is considering being pregnant during the study; * History of other malignancies, including hematological tumors, solid tumors except hepatobiliary system; * History of infectious diseases, including hepatis A, B, C, E and tuberculosis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The percentage of new occurrence of decompensated liver related events, malignancies, liver transplantation and liver-related death caused by PSC and IgG4-SC | 1 year | describe the characteristics and clinical outcomes of PSC and IgG4-SC patients among multiple medical centers in China |
Countries
China
Contacts
Primary ContactMin Lian, MD, PhD
Outcome results
None listed