Impact of Catch-up HPV Vaccination

Impact of Catch-up HPV Vaccination on the Development of Cervical Lesions

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05462249

Acronym

HPVAC2

Enrollment

354

Registered

2022-07-18

Start date

2021-05-21

Completion date

2022-06-30

Last updated

2025-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer, Cervical Lesion, HPV, HPV Vaccination, Vaccine Preventable Disease

Brief summary

Each year in France, more than 6000 new cases of HPV inducted cancers are recorded. The vaccinal cover stays insufficient since less than 30% of the french population is vaccinated. Therefore french studies about vaccine efficacy and especially about the catch-up vaccine (done after 15years old) are needed. HPVAC2 is a prospective, analytic and monocentric study designed to learn the impact of the catch-up HPV vaccination. Women from 25 years old and born after 1984 may be included if they come to the Brest CHU to do their regular cervical smear. At this time, a survey will be given to know their vaccinal status. The aim of the study is to prove the efficacy of the catch up vaccination by analyzing the cervical smears results and by comparing the vaccinated group with the not-vaccinated group.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 38 Years

Healthy volunteers

Yes

Inclusion criteria

* Age limit * Patient must have done a HPV or smear test during the study period * Consent necessary

Exclusion criteria

* Age limit * No HPV or smear test done in the study period * Patient not able to give her consent

Design outcomes

Primary

Measure	Time frame	Description
Test HPV and smear test result.	13 months.	Study the effectiveness of anti-HPV vaccine (done between 15 and 19 years old).

Secondary

Measure	Time frame	Description
Test HPV and smear test result.	13 months.	Study the effectiveness of anti-HPV vaccine (done between 11 and 15 years old).
Test HPV and smear test result regarding the cervical cancer risk factors.	13 months.	Study the impact of the known cervical cancer risk factors on the smear results.

Countries

France

Outcome results