Gastric Cancer Screening
Conditions
Brief summary
The Kimura-Takamoto classification established in Japan can observe the extent of gastric atrophy in real-time under endoscopy, and diffuse atrophy also indicates an increased risk of gastric cancer. Recent studies have found that the evaluation of intestinal metaplasia score (EGGIM score) of various stomach parts by electronic staining can well identify OLGIM III\\ IV patients. Although the Kimura-Takamoto classification and EGGIM score can evaluate the risk of gastric cancer in patients, only in cross-sectional studies, it is not clear the diagnostic value of risk assessment in population screening. Early gastric cancer has the characteristics of hidden lesions and a high rate of clinical missed diagnosis. Concentrating high-risk groups through risk scores is expected to guide endoscopic doctors to conduct a targeted careful examination. However, it is not clear whether Kimura-Takamoto classification and EGGIM score can improve the detection rate of early gastric cancer in clinical practice.
Interventions
PROCEDUREKimura-Takemoto classification
All patients were given two risk scores, the order of which was randomly determined.
PROCEDUREEGGIM
All patients were given two risk scores, the order of which was randomly determined.
Sponsors
Yanqing Li
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged 40-80 years undergoing gastroscopy * Patients intend to undergo ESD treatment
Exclusion criteria
* patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychiatric disorders who cannot participate in gastroscopy * Patients with previous surgical procedures on the stomach * patients with contraindications to biopsy * Patients who refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Early gastric cancer detection rate | 36 months | The detection rate of early gastric cancer |
Countries
China
Contacts
Primary ContactYan-qing Li
Outcome results
None listed