Brain Trauma
Conditions
Keywords
Soccer, Heading, Omega-3, Neurofilament Light, Subconcussive, Women
Brief summary
The purpose of this study is to (1) assess how a competitive season of purposeful gameplay soccer heading in collegiate women soccer players is related to a blood biomarker for sports-related brain injury, plasma neurofilament light (NF-L), and (2) examine how a player's omega-3 status is related to plasma NF-L concentration changes during and after a competitive season of gameplay soccer heading.
Interventions
OTHERPlasma Neurofilament Light (NF-L)
Plasma NF-L is a biomarker of axonal brain injury following sports-related head impacts.
OTHEROmega-3 Index
Omega-3 Index is the omega-3 fatty acid content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) within the erythrocyte cell membrane. It is expressed as EPA+DHA as a percent of total identified fatty acids.
OTHERHeadCount Questionnaire
HeadCount is a web-based, structured, self-administered questionnaire to assess longer-term heading exposure during competitive play and is administered bi-weekly.
Sponsors
University of Kansas Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
* At least 18 years of age. * Active player on the university's current team roster for the upcoming competitive season. * Is eligible to participate in games and is not redshirting.
Exclusion criteria
* Is recovering from a Physician diagnosed concussion. * Is recovering from another injury prohibiting the study participant from participating in all sport-related activities.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in plasma neurofilament light concentrations from baseline, during, and after a competitive season. | Baseline, 1 Months, 2 Months, 3 Months, 6 Months | Plasma neurofilament light (pg/mL) is a biomarker of axonal brain injury following sports-related head impacts. |
| Change in purposeful soccer heading frequencies from baseline, during, and after a competitive season. | Baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 10 weeks, 12 weeks, 14 weeks | HeadCount is a web-based, structured, self-administered questionnaire to assess longer-term heading frequencies (#) during competitive play and is administered bi-weekly. |
| Change in Omega-3 status from baseline, during, and after a competitive season. | Baseline, 1 Months, 2 Months, 3 Months, 6 Months | Omega-3 Index (%) is the omega-3 fatty acid content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) within membrane of red blood cell. It is expressed as EPA+DHA as a percent of total identified fatty acids. |
Countries
United States
Outcome results
None listed