Knee Osteoarthritis
Conditions
Brief summary
The aim of the study to investigate the relationship between femoral cartilage thickness in Ultrasonographic evaluation and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis
Detailed description
Aim: The aim of the study is to investigate the relationship between femoral cartilage thickness and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis. Methods: This study is designed as a prospective, cross-sectional trial. 90 participants aged between 50-65 years with knee osteoarthritis(OA) and at least 50 participants without any symptom for knee OA are included in the study in accordance with the inclusion criteria. Participants' demographic characteristics will be evaluated, and ultrasonographic measurement will be performed for measuring femoral cartilage thickness. Visual Analog scale will be used for pain severity and Western Ontario and McMaster Universities Osteoartrit index (WOMAC) will be used for assessing functionality of the patients. Also hematologic parameters(neutrophils, leucocytes, lymphocytes, platelet, CRP, erythrocyte sedimentation rate) will be evaluated for investigating the inflammation. The relationship between femoral cartilage thickness and inflammatory parameters, pain severity and functionality in knee osteoarthritis will be analysed for both group.
Interventions
DIAGNOSTIC_TESTultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality
ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality
Sponsors
Kanuni Sultan Suleyman Training and Research Hospital
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* diagnosed as knee osteoarthritis * aged between 50-65 years * volunteer to participate in the study
Exclusion criteria
* limitation of cooperation * moderate to severe dementia or mental retardation, which may cause limitations in examination, testing and treatment * refusal to participate in the study * pprevious total knee prosthesis surgery * secondary osteoarthritis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ultrasonography | 1 day | measurement of femoral cartilage thickness |
| Visual Analog Scale | 1 day | evaluation of pain severity |
| Western Ontario and McMaster Universities Osteoarthritis Index | 1 day | evaluation of functionality |
| neutrophil account | 1 day | neutrophil account |
| lymphocyte account | 1 day | lymphocyte account |
| monocyte account | 1 day | monocyte account |
| platelet account | 1 day | platelet account |
| eritrocyte sedimentation rate | 1 day | eritrocyte sedimentation rate |
| C-reactive protein | 1 day | C-reactive protein |
Countries
Turkey (Türkiye)
Contacts
Primary ContactMerve D. Korkmaz, M.D.
Outcome results
None listed