Sarcopenia, Stroke
Conditions
Brief summary
The aim of this study is to propose a new measurement point for temporal muscle thickness (TMT) that can be similarly localized in computerized tomography (CT) /magnetic resonance imaging (MRI) and ultrasonography (USG), and to evaluate the reliability and consistency of these measurements.
Detailed description
Recently, temporal muscle thickness (TMT) has been proposed as a new marker of whole-body muscle function. In addition, TMT has been shown to be a useful parameter for estimating skeletal muscle mass. Measurement of temporal muscle mass with CT and MRI has been studied in the literature in recent years. All stroke patients undergo cranial CT or MRI examinations at the time of admission. However, the literature indicates that USG can also be used to measure temporal muscle thickness. The recommended measurement points for CT, MRI, or USG in the studies performed to date depend on the particular imaging modality, and it does not seem possible to use them interchangeably. The aim of this study is to propose a new TMT measurement point that can be localized in a similar way in CT /MRI and USG, and to evaluate the reliability and agreement of these measurements.
Interventions
None listed
Sponsors
Bozyaka Training and Research Hospital
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Referral to the radiology department for an MRI or CT scan
Exclusion criteria
* Medically unstable condition (presence or high risk of impaired consciousness, respiration, or circulation). * Vulnerable populations (patients with a terminal illness, people living in nursing homes, unemployed or poor people, people in need of urgent medical care, children, people unable to consent, etc.).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intra-rater reliability of ultrasonographic TMT measurement. | Baseline | The intraclass correlation coefficient (ICC) of the two measurements performed by the physiatrist will be calculated using the Two-way mixed effects, absolute agreement, single rater/measurement model. |
| Inter-rater reliability of ultrasonographic TMT measurement. | Baseline | Intraclass correlation coefficients of TMT measurements performed by the radiologist and physiatrist will be calculated using the Two-way mixed effects, absolute agreement, multiple raters/measurements model. |
| Inter-rater reliability of TMT measurements of MRI and CT | Baseline | Intraclass correlation coefficients of TMT measurements performed by the radiologist and physiatrist will be calculated using the Two-way mixed effects, absolute agreement, single rater/measurement model. |
| Agreement of ultrasonographic TMT measurement with MRI and CT measurements. | Baseline | The intraclass correlation coefficient of the measurements will be calculated using the two-way mixed effects, absolute agreement, multiple raters/measurements model. In addition, the agreement of the measurements will be evaluated using the Bland-Altman method. Furthermore, the Technical Error of Measurement (TEM) will be calculated. |
Countries
Turkey (Türkiye)
Outcome results
None listed